Project detail

Shaping of skeletal elements during regeneration of salamander limbs by X-ray computed microtomography

Duration: 01.03.2021 — 28.02.2022

Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2021-01-01 - 2022-12-31)

On the project

Limb regeneration in salamanders is a unique example for regeneration of a complex body part. The regeneration in salamanders is a well-established model system. However, cell dynamics of shaping during skeletal morphogenesis remain unclear. In this work, X-ray computed microtomography will be used to characterize the formation of skeletal elements during salamander development and regeneration. This could provide novel explanations of how the rod-shaped cartilages grow and acquire their shape under different constraints and conditions.

Mark

CEITEC VUT-J-21-7145

Default language

Czech

People responsible

Zikmund Tomáš, doc. Ing., Ph.D. - fellow researcher
Kaiser Markéta, Ing., Ph.D. - principal person responsible

Units

Advanced instrumentation and methods for material characterization
- internal (2021-01-01 - 2021-12-31)
Central European Institute of Technology BUT
- beneficiary (2021-01-01 - 2021-12-31)

Results

TESAŘOVÁ, M.; MANCINI, L.; MAURI, E.; ALJANČIČ, G.; NĂPĂRUŞ-ALJANČIČ, M.; KOSTANJŠEK, R.; BIZJAK MALI, L.; ZIKMUND, T.; KAUCKÁ, M.; PAPI, F.; GOYENS, J.; BOUCHNITA, A.; HELLANDER, A.; ADAMEYKO, I.; KAISER, J. Living in darkness: Exploring adaptation of Proteus anguinus in 3 dimensions by X-ray imaging. GigaScience, 2022, vol. 11, no. 5, p. 1-8. ISSN: 2047-217X.
Detail

Responsibility: Kaiser Markéta, Ing., Ph.D.