Project detail

Smart synthetic hydrogels for 4D bioprinting

Duration: 01.03.2023 — 28.02.2024

Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2023-01-01 - 2024-12-31)

On the project

Smart 4D printed hydrogels enriched with human dermal fibroblasts (HDF) cells promise a great application in tissue engineering to produce pharmaceuticals and medical implants. This project uses a bioresorbable hydrogel PLGA-PEG-PLGA modified with double bonds (blue-light crosslinking) and thiol groups (pH crosslinking). The possibility of crosslinking the hydrogel by stimuli after 3D printing presents the time factor of 4D printing. Cytocompatibility, stability, mechanical properties and strength of printed hydrogel carriers will be evaluated.

Mark

CEITEC VUT-J-23-8187

Default language

Czech

People responsible

Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher
Tušlová Klára, Ing. - principal person responsible

Units

Advanced Biomaterials
- beneficiary (2023-01-01 - 2023-12-31)
Central European Institute of Technology BUT
- responsible department (2023-01-12 - 2023-03-06)

Results

CHAMRADOVÁ, I.; LYSÁKOVÁ, K.; KADLECOVÁ, Z.; VOJTOVÁ, L. Vývoj biokompatibilního “smart” hydrogelu uvolňujícího fibroblastový růstový faktor. III. česko-slovenský kongres "MEZIOBOROVÉ PŘÍSTUPY V HOJENÍ RAN“. Brno: SYMMA, spol. s r.o., 2023. s. 28-28. ISBN: 978-80-11-04155-7.
Detail

LYSÁKOVÁ, K.; SAHUĽ, M.; FINNE-WISTRAND, A.; VOJTOVÁ, L. Exploring the potential of 4D bioprinting of smart PLGA-PEG-PLGA based hydrogel for personalized medicine. THE TWENTY-FOURTH ANNUAL CONFERENCE YUCOMAT 2023 Program and Book of Abstracts. Belgrade: Materials Research Society of Serbia, 2023. p. 175-175. ISBN: 978-86-919111-8-8.
Detail

Responsibility: Tušlová Klára, Ing.