Project detail

Stabilization of nature-derived antimicrobial and pro-healing extracts for acute and chronic wound healing

Duration: 01.03.2023 — 28.02.2024

Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2023-01-01 - 2024-12-31)

On the project

Diabetic foot ulcer is an unpleasant chronic wound, that ican no longer be treated by conventional antibiotics due to the antibiotic resistance of the bacteria present. In this project, several nature-derived extracts will be prepared and tested on their antimicrobial and pro-healing properties. Extracts will be stabilized via encapsulation into nanoparticles to improve their stability release. A bioresorbable, and injectable hydrogel based on furcellaran will serve as a carrier for the drug delivery of bioactive nanoparticles.

Mark

CEITEC VUT-J-23-8420

Default language

Czech

People responsible

Rychetský Matěj, Ing. - fellow researcher
Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher
Kadlecová Zuzana, Ing. - principal person responsible

Units

Advanced Biomaterials
- beneficiary (2023-01-01 - 2023-12-31)
Central European Institute of Technology BUT
- responsible department (2023-01-31 - 2023-03-06)

Results

KADLECOVÁ, Z.; RYCHETSKÝ, M.; VÍTOVÁ, E.; VOJTOVÁ, L. Preparation of Liposome-enriched system for Controlled Release of Calendula Officinalis Extract in DFU Treatment. THE TWENTY-FOURTH ANNUAL CONFERENCE YUCOMAT 2023 Program and Book of Abstracts Herceg Novi, September 4-8, 2023. 1. Belgrade: Materials Research Society of Serbia, 2023. p. 111-111. ISBN: 978-86-919111-8-8.
Detail

CHAMRADOVÁ, I.; LYSÁKOVÁ, K.; KADLECOVÁ, Z.; VOJTOVÁ, L. Vývoj biokompatibilního “smart” hydrogelu uvolňujícího fibroblastový růstový faktor. III. česko-slovenský kongres "MEZIOBOROVÉ PŘÍSTUPY V HOJENÍ RAN“. Brno: SYMMA, spol. s r.o., 2023. s. 28-28. ISBN: 978-80-11-04155-7.
Detail

RYCHETSKÝ, M.; KADLECOVÁ, Z.; VÍTOVÁ, E.; VOJTOVÁ, L. Maximizing the potential of natural antimicrobial and antioxidant extracts for food application. 3rd Food Chemistry Conference, Dresden; Book of abstracts. Dresden: 2023. p. 168-168.
Detail

Responsibility: Kadlecová Zuzana, Ing.