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BLAŽKOVÁ, I. NGUYEN, H. DOSTÁLOVÁ, S. KOPEL, P. STANISAVLJEVIC, M. VACULOVIČOVÁ, M. STIBOROVÁ, M. ECKSCHLAGER, T. KIZEK, R. ADAM, V.
Original Title
Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery
Type
journal article in Web of Science
Language
English
Original Abstract
Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution
Keywords
Magnetic particle, doxorubicin, fluorescence spectroscopy,
Authors
BLAŽKOVÁ, I.; NGUYEN, H.; DOSTÁLOVÁ, S.; KOPEL, P.; STANISAVLJEVIC, M.; VACULOVIČOVÁ, M.; STIBOROVÁ, M.; ECKSCHLAGER, T.; KIZEK, R.; ADAM, V.
RIV year
2013
Released
27. 6. 2013
Publisher
MDPI
ISBN
1422-0067
Periodical
International Journal of Molecular Sciences
Year of study
14
Number
7
State
Swiss Confederation
Pages from
13391
Pages to
13402
Pages count
11
URL
http://www.mdpi.com/1422-0067/14/7/13391
Full text in the Digital Library
http://hdl.handle.net/11012/70079
BibTex
@article{BUT100937, author="Iva {Blažková} and Hoai Viet {Nguyen} and Simona {Dostálová} and Pavel {Kopel} and Maja {Stanisavljevic} and Markéta {Vaculovičová} and Marie {Stiborová} and Tomáš {Eckschlager} and René {Kizek} and Vojtěch {Adam}", title="Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery", journal="International Journal of Molecular Sciences", year="2013", volume="14", number="7", pages="13391--13402", doi="10.3390/ijms140713391", issn="1422-0067", url="http://www.mdpi.com/1422-0067/14/7/13391" }