Publication detail

Sarcosine as a potential prostate cancer biomarker – A review

CERNEI, N. HEGER, Z. GUMULEC, J. ZÍTKA, O. MASAŘÍK, M. BABULA, P. ECKSCHLAGER, T. STIBOROVÁ, M. KIZEK, R. ADAM, V.

Original Title

Sarcosine as a potential prostate cancer biomarker – A review

Type

journal article in Web of Science

Language

English

Original Abstract

Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that fact, there is great interest in the finding of new markers including amino acids, proteins or nucleic acids. Prostate specific antigen (PSA) is commonly used and is the most important biomarker of CaP. This marker can only be detected in blood and its sensitivity is approximately 80%. Moreover, early stages cannot be diagnosed using this protein. Currently, there does not exist a test for diagnosis of early stages of prostate cancer. This fact motivates us to find markers sensitive to the early stages of CaP, which are easily detected in body fluids including urine

Keywords

Prostate cancer, markers, prostate specific antigen, biomarker, urine

Authors

CERNEI, N.; HEGER, Z.; GUMULEC, J.; ZÍTKA, O.; MASAŘÍK, M.; BABULA, P.; ECKSCHLAGER, T.; STIBOROVÁ, M.; KIZEK, R.; ADAM, V.

RIV year

2013

Released

4. 7. 2013

Publisher

MDPI

ISBN

1422-0067

Periodical

International Journal of Molecular Sciences

Year of study

14

Number

7

State

Swiss Confederation

Pages from

13893

Pages to

13908

Pages count

15

URL

http://www.mdpi.com/1422-0067/14/7/13893

Full text in the Digital Library

http://hdl.handle.net/11012/70084

BibTex

@article{BUT100938,
  author="Natalia Vladimirovna {Cernei} and Zbyněk {Heger} and Jaromír {Gumulec} and Ondřej {Zítka} and Michal {Masařík} and Petr {Babula} and Tomáš {Eckschlager} and Marie {Stiborová} and René {Kizek} and Vojtěch {Adam}",
  title="Sarcosine as a potential prostate cancer biomarker – A review",
  journal="International Journal of Molecular Sciences",
  year="2013",
  volume="14",
  number="7",
  pages="13893--13908",
  doi="10.3390/ijms140713893",
  issn="1422-0067",
  url="http://www.mdpi.com/1422-0067/14/7/13893"
}