Publication detail

Ultrasound perfusion analysis combining bolus-tracking and burst-replenishment

JIŘÍK, R. NYLUND, K. GILJA, O. MÉZL, M. HARABIŠ, V. KOLÁŘ, R. STANDARA, M. TAXT, T.

Original Title

Ultrasound perfusion analysis combining bolus-tracking and burst-replenishment

Type

journal article - other

Language

English

Original Abstract

A new signal model and processing method for quantitative ultrasound perfusion analysis is presented, called bolus-and-burst. The method has the potential to provide absolute values of blood flow, blood volume, and mean transit time. Furthermore, it provides an estimate of the local arterial input function which characterizes the arterial tree, allowing accurate estimation of the bolus arrival time. The method combines two approaches to ultrasound perfusion analysis: bolus-tracking and burst-replenishment. A pharmacokinetic model based on the concept of arterial input functions and tissue residue functions is used to model both the bolus and replenishment parts of the recording. The pharmacokinetic model is fitted to the data using blind deconvolution. A preliminary assessment of the new perfusion-analysis method is presented on clinical recordings.

Keywords

quantitative ultrasound perfusion analysis, replenishment, blood flow, contrast agent

Authors

JIŘÍK, R.; NYLUND, K.; GILJA, O.; MÉZL, M.; HARABIŠ, V.; KOLÁŘ, R.; STANDARA, M.; TAXT, T.

RIV year

2013

Released

1. 2. 2013

ISBN

0885-3010

Periodical

IEEE Transactions on Ultrasonocs, Ferroelectrics, and Frequency Control

Year of study

60

Number

2

State

United States of America

Pages from

310

Pages to

319

Pages count

10

BibTex

@article{BUT102230,
  author="Radovan {Jiřík} and Kim {Nylund} and Odd Helge {Gilja} and Martin {Mézl} and Vratislav {Harabiš} and Radim {Kolář} and Michal {Standara} and Torfinn {Taxt}",
  title="Ultrasound perfusion analysis combining bolus-tracking and burst-replenishment",
  journal="IEEE Transactions on Ultrasonocs, Ferroelectrics, and Frequency Control",
  year="2013",
  volume="60",
  number="2",
  pages="310--319",
  issn="0885-3010"
}