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JANŮ, L. STANISAVLJEVIC, M. KŘÍŽKOVÁ, S. ŠOBROVÁ, P. VACULOVIČOVÁ, M. KIZEK, R. ADAM, V.
Original Title
Electrophoretic study of peptide-mediated quantum dot-human immunoglobulin bioconjugation
Type
journal article in Web of Science
Language
English
Original Abstract
The bioconjugation of quantum dots (QDs) is a key process in their application for bioanalysis as well as imaging. The coupling of QDs with biologically active molecules such as peptides, nucleic acids, and/or antibodies enables their fluorescent labeling, and therefore, selective and sensitive tracking during the bioanalytical process, however, the efficiency of the labeling and preservation of the biological activity of the bioconjugate have to be considered. In this study, a new approach of the bioconjugation of CdTe-QDs and human immunoglobulin employing a small peptide is described
Keywords
Antibody, Bioconjugation, Gel electrophoresis, Immunoglobulin, Quantum dot
Authors
JANŮ, L.; STANISAVLJEVIC, M.; KŘÍŽKOVÁ, S.; ŠOBROVÁ, P.; VACULOVIČOVÁ, M.; KIZEK, R.; ADAM, V.
RIV year
2013
Released
1. 9. 2013
ISBN
0173-0835
Periodical
Electrophoresis
Year of study
34
Number
18
State
Federal Republic of Germany
Pages from
2725
Pages to
2732
Pages count
8
BibTex
@article{BUT103146, author="Libor {Janů} and Maja {Stanisavljevic} and Soňa {Křížková} and Pavlína {Adam} and Markéta {Vaculovičová} and René {Kizek} and Vojtěch {Adam}", title="Electrophoretic study of peptide-mediated quantum dot-human immunoglobulin bioconjugation", journal="Electrophoresis", year="2013", volume="34", number="18", pages="2725--2732", doi="10.1002/elps.201300088", issn="0173-0835" }