Publication detail

Nanostructured surface effect of electrode on doxorubicin determination

KYNCLOVÁ, H. PŘIBYL, J. HRDÝ, R. DRBOHLAVOVÁ, J. PRÁŠEK, J. HUBÁLEK, J.

Original Title

Nanostructured surface effect of electrode on doxorubicin determination

Type

conference paper

Language

English

Original Abstract

In this study, we compared two types of nanostructured electrodes with gold nanocolumns and flat gold electrodes by measurements with doxorubicin. Nanostructured electrodes were fabricated by electrochemical anodic oxidation followed by deposition of gold to the porous alumina. Flat gold electrodes were fabricated by physical evaporation of gold layer to the silicon substrate. All electrodes were characterized by electrochemical impedance spectroscopy and then the electrochemical determination of doxorubicin was studied by differential pulse voltammetry. The impedance spectroscopy measurements proved a bigger electroactive area for nanostructured electrodes. The gold nanocolumns have been found as an important factor in increasing of electrodes active area. This fact is very important for sensors sensitivity. Fabricated electrodes were successfully used for determination of doxorubicin.

Keywords

Doxorubicin, gold nanocolumns, nanostructured electrode, flat gold electrode, electrochemical impedance spectroscopy, differential pulse voltammetry, titanium dioxide

Authors

KYNCLOVÁ, H.; PŘIBYL, J.; HRDÝ, R.; DRBOHLAVOVÁ, J.; PRÁŠEK, J.; HUBÁLEK, J.

RIV year

2014

Released

13. 1. 2014

Publisher

Trans Tech Publications Inc.

Location

Switzerland

ISBN

978-3-03835-001-9

Book

4th International Conference on Nanotechnology and Biosensors

ISBN

1660-9336

Periodical

Applied Mechanics and Materials

Year of study

490-491

Number

262

State

Swiss Confederation

Pages from

262

Pages to

266

Pages count

5

BibTex

@inproceedings{BUT104261,
  author="Hana {Kynclová} and Jakub {Přibyl} and Radim {Hrdý} and Jana {Drbohlavová} and Jan {Prášek} and Jaromír {Hubálek}",
  title="Nanostructured surface effect of electrode on doxorubicin determination",
  booktitle="4th International Conference on Nanotechnology and Biosensors",
  year="2014",
  journal="Applied Mechanics and Materials",
  volume="490-491",
  number="262",
  pages="262--266",
  publisher="Trans Tech Publications Inc.",
  address="Switzerland",
  doi="10.4028/www.scientific.net/AMM.490-491.262",
  isbn="978-3-03835-001-9",
  issn="1660-9336"
}