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KUPKA, V. VOJTOVÁ, L. JANČÁŘ, J.
Original Title
Synthesis and Characterization of Polyurethane Elastomers Based on Poly(ethylene glycol) and Poly(caprolactone) with Potential Use in Medicine
Type
abstract
Language
English
Original Abstract
Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzed with stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or hydrophobic PCL, were synthesized as well. Effect of bio-PU composition on the swelling and hydrolytic stability was investigated together with testing mechanical properties of prepared samples. Chemical composition was evaluated by infrared spectroscopy and the degree of conversion was measured by extraction of the specimens in acetone. Thermal stability was measured by thermogravimetric analysis and differential scanning calorimetry (DSC) was used to observe thermal properties such as glass transition and melting temperature.
Keywords
polyurethane, elastomer, bioresorbable, poly(ethylene glycol), poly(caprolactone)
Authors
KUPKA, V.; VOJTOVÁ, L.; JANČÁŘ, J.
Released
1. 11. 2013
Publisher
Future Medicine
Location
London
ISBN
1746-0751
Periodical
Regenerative Medicine
Year of study
8
Number
6s
State
United Kingdom of Great Britain and Northern Ireland
Pages from
190
Pages to
Pages count
426
BibTex
@misc{BUT104596, author="Vojtěch {Kupka} and Lucy {Vojtová} and Josef {Jančář}", title="Synthesis and Characterization of Polyurethane Elastomers Based on Poly(ethylene glycol) and Poly(caprolactone) with Potential Use in Medicine", year="2013", journal="Regenerative Medicine", volume="8", number="6s", pages="190--190", publisher="Future Medicine", address="London", doi="10.3390/molecules22071107", issn="1746-0751", note="abstract" }