Publication detail

Synthesis and Characterization of Polyurethane Elastomers Based on Poly(ethylene glycol) and Poly(caprolactone) with Potential Use in Medicine

KUPKA, V. VOJTOVÁ, L. JANČÁŘ, J.

Original Title

Synthesis and Characterization of Polyurethane Elastomers Based on Poly(ethylene glycol) and Poly(caprolactone) with Potential Use in Medicine

Type

abstract

Language

English

Original Abstract

Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzed with stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or hydrophobic PCL, were synthesized as well. Effect of bio-PU composition on the swelling and hydrolytic stability was investigated together with testing mechanical properties of prepared samples. Chemical composition was evaluated by infrared spectroscopy and the degree of conversion was measured by extraction of the specimens in acetone. Thermal stability was measured by thermogravimetric analysis and differential scanning calorimetry (DSC) was used to observe thermal properties such as glass transition and melting temperature.

Keywords

polyurethane, elastomer, bioresorbable, poly(ethylene glycol), poly(caprolactone)

Authors

KUPKA, V.; VOJTOVÁ, L.; JANČÁŘ, J.

Released

1. 11. 2013

Publisher

Future Medicine

Location

London

ISBN

1746-0751

Periodical

Regenerative Medicine

Year of study

8

Number

6s

State

United Kingdom of Great Britain and Northern Ireland

Pages from

190

Pages to

190

Pages count

426

BibTex

@misc{BUT104596,
  author="Vojtěch {Kupka} and Lucy {Vojtová} and Josef {Jančář}",
  title="Synthesis and Characterization of Polyurethane Elastomers Based on Poly(ethylene glycol) and Poly(caprolactone) with Potential Use in Medicine",
  year="2013",
  journal="Regenerative Medicine",
  volume="8",
  number="6s",
  pages="190--190",
  publisher="Future Medicine",
  address="London",
  doi="10.3390/molecules22071107",
  issn="1746-0751",
  note="abstract"
}