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MOHAMED, F. SOLIMAN, A. ABDEL-MOTALEB, R. ABDEL-RAHMAN, R. ABDEL-LATTIF, A. FOUDA, M. AL-DEYAB, S. MOHAMED, A.
Original Title
Synthesis and antibacterial activity of 3-arylidene chromen-2, 4-dione derivatives
Type
journal article - other
Language
English
Original Abstract
Derivatives of 3-arylidene chromen-2, 4-dione 1 were synthesized to be used as a starting material for synthesizing some new fused heterocyclic compounds containing coumarin moiety. When compounds 1 reacted with hydrazine derivatives, hydroxylamine hydrochloride, urea, thiourea, semicarbazide and thiosemicarbazide it gave the corresponding compounds 2-5. Compound 4a, b reacted with methyl iodide in DMF and K2CO3 at room temperature to afford the corresponding 6a, b. All these compounds were screened InVitro for their antibacterial activity.
Keywords
Coumarin, hydrazine, pyrazol, isoxazol, pyrimidine and antibacterial activity
Authors
MOHAMED, F.; SOLIMAN, A.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; MOHAMED, A.
RIV year
2013
Released
7. 11. 2013
ISBN
1097-8135
Periodical
Life Science Journal
Year of study
10
Number
4
State
People's Republic of China
Pages from
840
Pages to
845
Pages count
6
BibTex
@article{BUT106169, author="F. K. {Mohamed} and A. Y. {Soliman} and Ramadan M. {Abdel-Motaleb} and Rasha M. {Abdel-Rahman} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Salem S. {Al-Deyab} and Asmaa S. {Mohamed}", title="Synthesis and antibacterial activity of 3-arylidene chromen-2, 4-dione derivatives", journal="Life Science Journal", year="2013", volume="10", number="4", pages="840--845", issn="1097-8135" }