Publication detail

Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives

SOLIMAN, A. MOHAMED, F. ABDEL-MOTALEB, R. ABDEL-RAHMAN, R. ABDEL-LATTIF, A. FOUDA, M. AL-DEYAB, S. MOHAMED, A.

Original Title

Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives

Type

journal article in Web of Science

Language

English

Original Abstract

2a,b, 3a,b ),(3 -acetyl-4-aryl -2-methyl-5-oxo-chromeno[3,2-c]2,3,4- trihydropyran 4a,b ), ( 2-amino-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile 5a,b and 2-amino-5-oxo-3,4,4a,10b-tetrahydro-2H,5H-pyrano[3,2-c]chromene-3-carboxylic acid amide 6a,b) were synthesized starting from 3-arylidene chromen-2,4-dione derivatives. The structures of the obtained compounds were confirmed by analytical elemental analysis, IR, 1H-NMR and mass spectra. The new compounds were screened for their antibacterial activity .Compound 3a was the most active compound against gram positive and gram negative bacteria.

Keywords

antibacterial, synthesis, coumarin drerivatives, IR, NMR, MS

Authors

SOLIMAN, A.; MOHAMED, F.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; MOHAMED, A.

RIV year

2013

Released

1. 11. 2013

ISBN

0973-7510

Periodical

Journal of Pure and Applied Microbiology

Year of study

7

Number

1

State

Republic of India

Pages from

435

Pages to

439

Pages count

5

BibTex

@article{BUT106195,
  author="A. Y. {Soliman} and F. K. {Mohamed} and Ramadan M. {Abdel-Motaleb} and Rasha M. {Abdel-Rahman} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Salem S. {Al-Deyab} and Asmaa S. {Mohamed}",
  title="Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives",
  journal="Journal of Pure and Applied Microbiology",
  year="2013",
  volume="7",
  number="1",
  pages="435--439",
  issn="0973-7510"
}