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PILGROVÁ, T. PEKAŘ, M.
Original Title
STABILITY OF THE COMPLEX NANOPARTICLES OF NEGATIVELY CHARGED HYALURONAN AND CATIONIC SURFACTANT
Type
conference paper
Language
English
Original Abstract
The aim of our study was to prepare hyaluronic acid nanoparticles based on electrostatic interactions with oppositely charged molecules and study stability of these particles under different conditions. Time and temperature stability, effect of ionic strength, effect of dilution of the system and effect of molecular weight of hyaluronan were investigated using fluorescence spectroscopy and dynamic light scattering methods. Fluorescence and dynamic light scattering experiments indicate that hyaluronan-surfactant nanoparticles are influenced by a whole range of aspects, such as temperature, ionic strength of solution and storage time while molecular weight of hyaluronan affect these system at least.
Keywords
Hyaluronan, surfactant, stability, fluorescence spectroscopy, dynamic light scattering
Authors
PILGROVÁ, T.; PEKAŘ, M.
RIV year
2014
Released
5. 11. 2014
Publisher
Tanger Ltd.
Location
Ostrava
ISBN
978-80-87294-55-0
Book
NANOCON 2014, Conference Proceedings
Edition
1st edition, 2014
Pages from
1
Pages to
5
Pages count
BibTex
@inproceedings{BUT110358, author="Tereza {Pilgrová} and Miloslav {Pekař}", title="STABILITY OF THE COMPLEX NANOPARTICLES OF NEGATIVELY CHARGED HYALURONAN AND CATIONIC SURFACTANT", booktitle="NANOCON 2014, Conference Proceedings", year="2014", series="1st edition, 2014", pages="1--5", publisher="Tanger Ltd.", address="Ostrava", isbn="978-80-87294-55-0" }