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HEGER, Z. SKALIČKOVÁ, S. ZÍTKA, O. ADAM, V. KIZEK, R.
Original Title
Apoferritin applications in nanomedicine
Type
journal article in Web of Science
Language
English
Original Abstract
Nanomedicine as a continuously evolving discipline is still looking for a structure with perfect properties that is usable as a multifunctional transporter. Great potential is attributed to synthetic materials such as fullerenes, porous hollow silica nanoparticles and single-wall nanotubes, among others. However, materials that are natural to the human body are more acceptable by the organism, and thus become an attractive approach in this field of research. Ferritins are proteins that naturally occur in most living organisms throughout evolution and may be a possible transporter choice. Numerous applications have demonstrated the possibilities of iron-free ferritins, called apoferritins, serving as platforms for various nanomedical purposes This article summarizes the advantages and disadvantages of these proteins and discusses their practical applications and future perspectives.
Keywords
horse spleen ferritin, magnetic resonance imaging, nanoscale, nanotrasporter, photodynamic therapy,self-assembly, therapeutic agents
Authors
HEGER, Z.; SKALIČKOVÁ, S.; ZÍTKA, O.; ADAM, V.; KIZEK, R.
RIV year
2014
Released
1. 1. 2014
ISBN
1743-5889
Periodical
Nanomedicine
Year of study
9
Number
14
State
United Kingdom of Great Britain and Northern Ireland
Pages from
2233
Pages to
2245
Pages count
13
BibTex
@article{BUT110991, author="Zbyněk {Heger} and Sylvie {Skaličková} and Ondřej {Zítka} and Vojtěch {Adam} and René {Kizek}", title="Apoferritin applications in nanomedicine", journal="Nanomedicine", year="2014", volume="9", number="14", pages="2233--2245", doi="10.2217/NNM.14.119", issn="1743-5889" }