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KREMPLOVÁ, M. FIALOVÁ, D. NEJDL, L. HYNEK, D. TRNKOVÁ, L. HUBÁLEK, J. KIZEK, R. ADAM, V.
Original Title
Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure
Type
journal article in Web of Science
Language
English
Original Abstract
The electroactivity of purine and pyrimidine bases is the most important property of nucleic acids that is very useful for determining oligonucleotides using square wave voltammetry. This study was focused on the electrochemical behavior of adenine-containing oligonucleotides before and after their isolation using paramagnetic particles. Two peaks were detecte - peak A related to the reduction of adenine base and another peak B involved in the interactions between individual adenine strands and contributes to the formation of various spatial structures. The influence of the number of adenine bases in the strand in the isolation process using paramagnetic particles was investigated too.
Keywords
adenine; adenine interaction; magnetic beads; square wave voltammetry; aptamer; biosensor; nanobiotechnology
Authors
KREMPLOVÁ, M.; FIALOVÁ, D.; NEJDL, L.; HYNEK, D.; TRNKOVÁ, L.; HUBÁLEK, J.; KIZEK, R.; ADAM, V.
RIV year
2014
Released
1. 3. 2014
Publisher
MDPI
ISBN
1996-1944
Periodical
Materials
Year of study
7
Number
3
State
Swiss Confederation
Pages from
1455
Pages to
1472
Pages count
18
URL
http://www.mdpi.com/1996-1944/7/3/1455
Full text in the Digital Library
http://hdl.handle.net/11012/63708
BibTex
@article{BUT111195, author="Monika {Kremplová} and Dana {Fialová} and Lukáš {Nejdl} and David {Hynek} and Libuše {Trnková} and Jaromír {Hubálek} and René {Kizek} and Vojtěch {Adam}", title="Influence of Magnetic Microparticles Isolation on Adenine Homonucleotides Structure", journal="Materials", year="2014", volume="7", number="3", pages="1455--1472", doi="10.3390/ma7031455", issn="1996-1944", url="http://www.mdpi.com/1996-1944/7/3/1455" }