Publication detail

Plasma-chemical modifications of cellulose for biomedical applications

PAVLIŇÁK, David, Veronika ŠVACHOVÁ, Libor VOJTEK, Jana ZARZYCKÁ, Pavel HYRŠL, Milan ALBERTI a Lucy VOJTOVÁ.

Original Title

Plasma-chemical modifications of cellulose for biomedical applications

Type

journal article in Web of Science

Language

English

Original Abstract

A 6-carboxycellulose (in medicine known as “oxidized cellulose” or “oxycellulose”) is one of the cellulose derivatives popular in the field of surgery. Health products based on oxidized cellulose are great local hemostatics with unique bactericidal and fully bioabsorbable effects. Traditional process of native cellulose oxidation is described as a complex radical reaction in strong acidic liquid medium doped by toxic nitrous radicals (NO*). Our plasma-chemical reaction demonstrates a new synthesis method of oxidized cellulose with unique bactericidal effect. This plasma-chemical treatment is based on atmospheric plasma discharge in liquid medium leading to the oxidation of polysaccharide molecules resulting in oxycellulose. Final oxycellulose properties were evaluated by infrared spectroscopy and carboxyl content determination. The biological impact showed a strong germicidal effect.

Keywords

oxidized cellulose, oxycellulose, antibacterial, plasma-chemical treatment, plasma

Authors

PAVLIŇÁK, David, Veronika ŠVACHOVÁ, Libor VOJTEK, Jana ZARZYCKÁ, Pavel HYRŠL, Milan ALBERTI a Lucy VOJTOVÁ.

RIV year

2014

Released

17. 11. 2014

Publisher

De Gruyter

ISBN

2391-5420

Periodical

Open Chemistry

Year of study

13

Number

1

State

Republic of Poland

Pages from

229

Pages to

335

Pages count

7

URL

http://www.degruyter.com/view/j/chem.2015.13.issue-1/chem-2015-0030/chem-2015-0030.xml?format=INT

BibTex

@article{BUT111998,
  author="David {Pavliňák} and Veronika {Pavliňáková} and Libor {Vojtek} and Jana {Zarzycká} and Pavel {Hyršl} and Milan {Alberti} and Lucy {Vojtová}",
  title="Plasma-chemical modifications of cellulose  for biomedical applications",
  journal="Open Chemistry",
  year="2014",
  volume="13",
  number="1",
  pages="229--335",
  doi="10.1515/chem-2015-0030",
  issn="2391-5420",
  url="http://www.degruyter.com/view/j/chem.2015.13.issue-1/chem-2015-0030/chem-2015-0030.xml?format=INT"
}