Přístupnostní navigace
E-application
Search Search Close
Publication detail
DIVIŠOVÁ, R. VÍTOVÁ, E. DIVIŠ, P. ZEMANOVÁ, J. OMELKOVÁ, J.
Original Title
Validation of SPME–GC–FID Method for Determination of Fragrance Allergens in Selected Cosmetic Products
Type
journal article in Web of Science
Language
English
Original Abstract
An analytical method for simultaneous determination of 24 legislatively restricted fragrance allergens in various cosmetic products was developed and validated using a combination of solid-phase microextraction and gas chromatography with flame ionization detector. The divinylbenzene-polydimethylsiloxane (DVB-PDMS) fiber was evaluated as the best for extraction of all studied fragrance allergens at 40oC and 20 min extraction time. All calibration curves showed good linearity in the range of 10-1 to 103 ug mL-1. Good repeatability and inter-day precision was determined for the proposed method. Detection limits for individual allergens ranged from 0.007 to 2.7 ug mL-1. The validated method was used to analyze real cosmetic samples. The obtained results indicated that not all of the analyzed cosmetic samples were labeled in accordance with European Cosmetic Directive.
Keywords
SPME, GC, fragrances, cosmetics
Authors
DIVIŠOVÁ, R.; VÍTOVÁ, E.; DIVIŠ, P.; ZEMANOVÁ, J.; OMELKOVÁ, J.
RIV year
2015
Released
5. 1. 2015
ISBN
1233-2356
Periodical
ACTA CHROMATOGRAPHICA
Year of study
27
Number
3
State
Republic of Poland
Pages from
509
Pages to
523
Pages count
15
URL
https://akademiai.com/doi/pdf/10.1556/AChrom.27.2015.3.8
BibTex
@article{BUT113399, author="Radka {Divišová} and Eva {Vítová} and Pavel {Diviš} and Jana {Zemanová} and Jiřina {Omelková}", title="Validation of SPME–GC–FID Method for Determination of Fragrance Allergens in Selected Cosmetic Products", journal="ACTA CHROMATOGRAPHICA", year="2015", volume="27", number="3", pages="509--523", doi="10.1556/AChrom.27.2015.3.8", issn="1233-2356", url="https://akademiai.com/doi/pdf/10.1556/AChrom.27.2015.3.8" }