Publication detail

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

NEUŽIL, P. Camila Campos, Wong, C, Soon, J. Reboud, J, Manz, A.

Original Title

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

Type

journal article in Web of Science

Language

English

Original Abstract

We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing system. We demonstrate different configurations to perform most detection schemes currently in use in LOC systems, including some of the most advanced such as nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and realtime PCR. The complete system is controlled by a single chip and the collected information is stored in situ, with the option of transferring the data to an external display by using a USB interface. In addition to providing a framework for truly portable real-life developments of LOC systems, we envisage that this system will have a significant impact on education, especially since it can easily demonstrate the benefits of integrated microanalytical systems.

Keywords

LOC, microTAS, PCR, electrochemistry, portable POC applications.

Authors

NEUŽIL, P. Camila Campos, Wong, C, Soon, J. Reboud, J, Manz, A.

RIV year

2014

Released

25. 3. 2014

Publisher

Royal Society of Chemistry

ISBN

1473-0197

Periodical

LAB ON A CHIP

Year of study

14

Number

2168

State

United Kingdom of Great Britain and Northern Ireland

Pages from

2168

Pages to

2176

Pages count

9

URL

http://pubs.rsc.org/en/Content/ArticleLanding/2014/LC/C4LC00310A

Full text in the Digital Library

http://hdl.handle.net/11012/61762

BibTex

@article{BUT115141,
  author="Pavel {Neužil}",
  title="From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)",
  journal="LAB ON A CHIP",
  year="2014",
  volume="14",
  number="2168",
  pages="2168--2176",
  doi="10.1039/c4lc00310a",
  issn="1473-0197",
  url="http://pubs.rsc.org/en/Content/ArticleLanding/2014/LC/C4LC00310A"
}