Publication detail

The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms

RICHTERA, L. CHUDOBOVÁ, D. ČÍHALOVÁ, K. KREMPLOVÁ, M. MILOSAVLJEVIĆ, V. KOPEL, P. BLAŽKOVÁ, I. HYNEK, D. ADAM, V. KIZEK, R.

Original Title

The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms

Type

journal article in Web of Science

Language

English

Original Abstract

The present experiment describes a synthesis process of composites based on graphene oxide, which was tested as a carrier for composites of metal- or metalloid-based nanoparticles (Cu, Zn, Mn, Ag, AgP, Se) and subsequently examined as an antimicrobial agent for some bacterial strains (Staphylococcus aureus (S. aureus), methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli (E. coli). The composites were first applied at a concentration of 300 μM on all types of model organisms and their effect was observed by spectrophotometric analysis, which showed a decrease in absorbance values in comparison with the control, untreated strain. The most pronounced inhibition (87.4%) of S. aureus growth was observed after the application of graphene oxide composite with selenium nanoparticles compared to control. Moreover, the application of the composite with silver and silver phosphate nanoparticles showed the decrease of 68.8% and 56.8%, respectively. For all the tested composites, the observed antimicrobial effect was found in the range of 26% to 87.4%. Interestingly, the effects of the composites with selenium nanoparticles significantly differed in Gram-positive (G+) and Gram-negative (G−) bacteria.

Keywords

Escherichia coli; graphene oxide; metal or semimetal based nanoparticles; Staphylococcus aureus; antibacterial effect

Authors

RICHTERA, L.; CHUDOBOVÁ, D.; ČÍHALOVÁ, K.; KREMPLOVÁ, M.; MILOSAVLJEVIĆ, V.; KOPEL, P.; BLAŽKOVÁ, I.; HYNEK, D.; ADAM, V.; KIZEK, R.

RIV year

2015

Released

1. 6. 2015

Publisher

MDPI

ISBN

1996-1944

Periodical

Materials

Year of study

8

Number

6

State

Swiss Confederation

Pages from

2294

Pages to

3011

Pages count

18

URL

http://www.mdpi.com/1996-1944/8/6/2994

Full text in the Digital Library

http://hdl.handle.net/11012/63713

BibTex

@article{BUT115884,
  author="Lukáš {Richtera} and Dagmar {Hegerová} and Kristýna {Číhalová} and Monika {Kremplová} and Vedran {Milosavljević} and Pavel {Kopel} and Iva {Blažková} and David {Hynek} and Vojtěch {Adam} and René {Kizek}",
  title="The Composites of Graphene Oxide with Metal or Semimetal Nanoparticles and Their Effect on Pathogenic Microorganisms",
  journal="Materials",
  year="2015",
  volume="8",
  number="6",
  pages="2294--3011",
  doi="10.3390/ma8062994",
  issn="1996-1944",
  url="http://www.mdpi.com/1996-1944/8/6/2994"
}