Publication detail

An Aditional Marker of Ventricular Dyssynchrony

JURÁK, P. HALÁMEK, J. PLEŠINGER, F. POSTRÁNECKÁ, T. LIPOLDOVÁ, J. NOVÁK, M. JURÁKOVÁ, K. LEINVEBER, P.

Original Title

An Aditional Marker of Ventricular Dyssynchrony

Type

conference paper

Language

English

Original Abstract

Patients suffering from left bundle branch block (LBBB) can be treated by resynchronization therapy (CRT). The QRS duration (QRSd) and QRS morphology are the main selection criteria. Unfortunately, approximately one-third of CRT patients are non-responders. Here we introduce an additional marker capable of distinguishing ventricular dyssynchrony more accurately. Methods: Ultra-high-frequency (UHF, sampling 25kHz) 12-lead ECG, 15-minute resting supine position, was measured. We analyzed 21 LBBB patients selected for CRT, the QRSd min/mean/max was 130/163/190 ms. Amplitude envelopes in the 500-1000 Hz passband were computed and averaged with R-wave trigger for each patient in V1 and V6 leads. V1-V6 dyssynchrony (DYS) was computed as the time difference between UHF amplitude maximums in the V1 and V6 QRS complex region. Results: The DYS parameter min/mean/max was 1/68/115 ms. Patients with a small value of the DYS parameter, in spite of its QRS duration meet CRT criteria (>120 ms), are not expected CRT responders. The DYS parameter indicates ventricular dyssynchrony and can potentially increase the percentage of CRT responders.

Keywords

Ventricular Dyssynchrony; Cardiac Resynchronization Therapy; Biventricular Pacemaker; Ultra-High-frequency ECG

Authors

JURÁK, P.; HALÁMEK, J.; PLEŠINGER, F.; POSTRÁNECKÁ, T.; LIPOLDOVÁ, J.; NOVÁK, M.; JURÁKOVÁ, K.; LEINVEBER, P.

Released

28. 8. 2015

ISBN

978-1-5090-0684-7

Book

Computing in Cardiology

ISBN

0276-6574

Periodical

Computers in Cardiology

Year of study

2015

Number

1

State

United States of America

Pages from

1

Pages to

4

Pages count

4

BibTex

@inproceedings{BUT116466,
  author="Pavel {Jurák} and Josef {Halámek} and Filip {Plešinger} and Tereza {Postránecká} and Jolana {Lipoldová} and Miroslav {Novák} and Kateřina {Juráková} and Pavel {Leinveber}",
  title="An Aditional Marker of Ventricular Dyssynchrony",
  booktitle="Computing in Cardiology",
  year="2015",
  journal="Computers in Cardiology",
  volume="2015",
  number="1",
  pages="1--4",
  doi="10.1109/CIC.2015.7408590",
  isbn="978-1-5090-0684-7",
  issn="0276-6574"
}