Publication detail

Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions

SZABÓ, Z. FIALA, P. LACINA, K. ŽÁK, J. VÁCLAVEK, T. SOPOUŠEK, J. ŽERAVÍK, J. SKLÁDAL, P.

Original Title

Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions

Type

journal article in Web of Science

Language

English

Original Abstract

A platform for electrochemical transduction suitable for miniaturised point-of-care diagnostic solutions with intuitive optical read-out was designed. Electrolytic current from electrochemical cell was transduced into the glow of a light-emitting diode. Its performance was optimised and several variants of transducing circuitry were tested. The circuit comprising field-effect transistor (FET) exhibited the sought abilities absolute simplicity and high and tuneable sensitivity of the transducing device. Limit-ofdetection, i.e. a signal readable by naked-eye without any additional instrumentation was as low as 4 mM for direct assay of H2O2. The whole transducing system employing FET consisted of 4 off-the-shelf components and its price reached <0.3 s even at small-scale experimental production. As our system was rather suitable for the semiquantitative “YES/NO” applications due to the steep response curve, an alternative circuitry for widening the linear range was also probed. Finally, rather higher initial voltage that was required in the electrochemical cell for FET-based transducer lead us to design a further simplified and more variable circuit employing the operational amplifier.

Keywords

Electrochemical transducer, transistor, operational amplifier, optical read-out, (bio)sensing

Authors

SZABÓ, Z.; FIALA, P.; LACINA, K.; ŽÁK, J.; VÁCLAVEK, T.; SOPOUŠEK, J.; ŽERAVÍK, J.; SKLÁDAL, P.

Released

6. 9. 2016

ISBN

0013-4686

Periodical

Electrochimica Acta

Number

216

State

United Kingdom of Great Britain and Northern Ireland

Pages from

147

Pages to

151

Pages count

5

URL

http://www.sciencedirect.com/science/article/pii/S0013468616319156

BibTex

@article{BUT127801,
  author="Zoltán {Szabó} and Pavel {Fiala} and Karel {Lacina} and Jaromír {Žák} and Tomáš {Václavek} and Jakub {Sopoušek} and Jiří {Žeravík} and Petr {Skládal}",
  title="Transistor Amplifier as an Electrochemical Transducer with Intuitive Optical Read-out: Improving Its Performance with Simple Electronic Solutions",
  journal="Electrochimica Acta",
  year="2016",
  number="216",
  pages="147--151",
  doi="10.1016/j.electacta.2016.09.028",
  issn="0013-4686",
  url="http://www.sciencedirect.com/science/article/pii/S0013468616319156"
}