Publication detail

Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States

LÓPEZ MOLINA, J. PLANELLS DEL POZO, E. FLOREA, D. FERNANDES, C. OSSO, B. ZALEWSKA, M. KŘÍŽKOVÁ, S. HEGER, Z. KIZEK, R. ADAM, V.

Original Title

Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States

Type

journal article in Web of Science

Language

English

Original Abstract

Zinc, an essential element playing crucial roles in numerous physiological, but also pathological processes, is still one of the most studied elements. The main importance of this metal is especially based on the structural role of zinc ions in many proteins including the transcription factors, antioxidant enzymes, and metallothioneins. Due to the role of zinc in many crucial physiological processes, its homeostasis must be intensively controlled. The controlling mechanisms are based especially on the zinc transporters and low-molecular proteins metallothioneins (MT). Zinc deficiency has been related with different state of diseases. Here, we primarily aim our attention to zinc and nutrition reviewing the whole process from intake to determination of this metal. The function of zinc ions in proteins with particular emphasis to oxidative stress is discussed followed by intake mechanisms and the role of zinc ions in both physiological and pathological processes. Finally, we summarized the assays used for detection of zinc in complex biological matrices.

Keywords

Zinc; biomarker; nutrition; health; disease; metallothionein; spectroscopy

Authors

LÓPEZ MOLINA, J.; PLANELLS DEL POZO, E.; FLOREA, D.; FERNANDES, C.; OSSO, B.; ZALEWSKA, M.; KŘÍŽKOVÁ, S.; HEGER, Z.; KIZEK, R.; ADAM, V.

Released

1. 6. 2016

ISBN

1452-3981

Periodical

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE

Year of study

11

Number

6

State

Republic of Serbia

Pages from

4470

Pages to

4496

Pages count

27

BibTex

@article{BUT128501,
  author="Jorge {López Molina} and Ellena {Planells del Pozo} and Daniela Ioana {Florea} and Carlos {Fernandes} and Bartolome Quintero {Osso} and Marta Barbara {Zalewska} and Soňa {Křížková} and Zbyněk {Heger} and René {Kizek} and Vojtěch {Adam}",
  title="Nutritional and Methodological Perspectives of Zinc Ions and Complexes - Physiological and Pathological States",
  journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE",
  year="2016",
  volume="11",
  number="6",
  pages="4470--4496",
  doi="10.20964/2016.06.38",
  issn="1452-3981"
}