Publication detail

Cross-interactions between TRKs receptors and neurotrophins: Insights from molecular docking and molecular dynamics

HADDAD, Y. ADAM, V. HEGER, Z.

Original Title

Cross-interactions between TRKs receptors and neurotrophins: Insights from molecular docking and molecular dynamics

Type

abstract

Language

English

Original Abstract

One of the major challenges in targeting Tyrosine Receptor Kinases (Trks) is the side effect resulting from simultaneous targeting of several Trk kinases at the same time. Thus, the aim of this work is to study the cross-interactions between Trks and neurotophins (NGF, NT3 and NT4/5) by comparative modeling.

Keywords

Neurotrophins; Trk kinases; Cross-interaction; Protein

Authors

HADDAD, Y.; ADAM, V.; HEGER, Z.

Released

30. 11. 2016

Publisher

Institute of molecular and translational medicine

Location

Olomouc, Czech Republic

ISBN

978-80-270-0464-5

Book

XII. Diagnostic, Predictive and Experimental Oncology Days

ISBN

2336-8284

Periodical

Diagnostic, Predictive and Experimental Oncology Days

State

Czech Republic

Pages from

38

Pages to

38

Pages count

1

BibTex

@misc{BUT133590,
  author="Yazan Abdulmajeed Eyadh {Haddad} and Vojtěch {Adam} and Zbyněk {Heger}",
  title="Cross-interactions between TRKs receptors and neurotrophins: Insights from molecular docking and molecular dynamics",
  booktitle="XII. Diagnostic, Predictive and Experimental Oncology Days",
  year="2016",
  journal="Diagnostic, Predictive and  Experimental Oncology Days",
  pages="38--38",
  publisher="Institute of molecular and translational medicine",
  address="Olomouc, Czech Republic",
  isbn="978-80-270-0464-5",
  issn="2336-8284",
  note="abstract"
}