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BORÁK, L. MARCIÁN, P.
Original Title
Bone Remodeling Algorithm Incorporating Various Quantities as Mechanical Stimulus and Assuming Initial Microcrack in Bone
Type
conference paper
Language
English
Original Abstract
It is widely accepted that bones have the ability to adapt to new biomechanical environment by changing their material properties, geometry and inner architecture. Bones have also an exceptional ability to self-repair, to remove microcracks and to prevent the bone damage caused by the fatigue failure. These abilities are enabled through coupled processes of bone resorption and bone formation, the processes collectively referred to as bone remodeling. Numerous studies have shown that bone remodeling is governed by combination of mechanical stimulus (strains) and its frequency, both sensed by sensor cells (osteocytes). Through mechanotransduction, the stimulus is transmitted to actor cells (osteoclasts, osteoblasts) that actually do the bone resorption or formation. Several theories have been proposed to predict bone remodeling and several finite-element-based algorithms have been introduced. The vast majority of them uses strain energy density as the mechanical stimulus. The purpose of this paper is to investigate and discuss the applicability of also other strain-based representations of the mechanical stimulus in simulations of remodeling of bone with an initial microcrack. The need for developing more reliable models is essential for both clinicians and engineers who are interested, for instance, in prediction of bone performance when various implants are involved.
Keywords
bone remodeling; strain; microdamage; mechano-regulation; finite element method
Authors
BORÁK, L.; MARCIÁN, P.
Released
1. 9. 2017
ISBN
1662-9795
Periodical
Key Engineering Materials (web)
Year of study
754
State
Swiss Confederation
Pages from
189
Pages to
193
Pages count
5
BibTex
@inproceedings{BUT138160, author="Libor {Borák} and Petr {Marcián}", title="Bone Remodeling Algorithm Incorporating Various Quantities as Mechanical Stimulus and Assuming Initial Microcrack in Bone", booktitle="Advances in Fracture and Damage Mechanics XVI", year="2017", journal="Key Engineering Materials (web)", volume="754", pages="189--193", doi="10.4028/www.scientific.net/KEM.754.189", issn="1662-9795" }