Publication detail

Effect of Different Doses of Organically Bound Selenium on Antioxidant Status and Levels of Metal Ions in Postpartum Sows

HORKÝ, P. RUTTKAY-NEDECKÝ, B. KREMPLOVÁ, M. KRYŠTOFOVÁ, O. KENŠOVÁ, R. HYNEK, D. BABULA, P. ZÍTKA, O. ZEMAN, L. ADAM, V. KIZEK, R.

Original Title

Effect of Different Doses of Organically Bound Selenium on Antioxidant Status and Levels of Metal Ions in Postpartum Sows

Type

journal article in Web of Science

Language

English

Original Abstract

The study was focused on the effect of different doses of organically bound selenium on antioxidant status in postpartum sows. 24 sows, Large White (English Large White) breed were divided into three balanced groups. Animals were fed with the basic feed ration containing selenium in the dose of 0.05 mg/kg feed mixture (FM). The first group of sows (n = 8) were fed without the addition of selenium into the diet and served as a control group. The second one (n = 8) received 0.30 mg Se/kg FM in the diet. The third group of sown were fed by selenium in the dose of 0.55 mg Se/kg FM. Antioxidant status and concentration of heavy metals in erythrocytes were monitored. Selenium in a dose of 0.30 mg/kg FM increased activities of antioxidant enzymes glutathione peroxidase by 12.4 % (P < 0.05) and glutathione-S-transferase by 17.6 % (P < 0.05). Higher antioxidant activity measured by FRAP (increase by 12.4 % (P < 0.05)), FR (by 12.9 % (P < 0.05)) and ABTS (by 10.2 % (P < 0.05)) methods was found. Reduced form of glutathione was increased for 27.0 % (P < 0.001). Concentration of selenium was increased by 51.7 % (P < 0.001). Content of cadmium was reduced by (16.3 % (P < 0.05)), on the other hand, content of copper was increased by 32.4 % (P < 0.001) in comparison with control group. Selenium in a dose of 0.55 mg/kg FM increased activities of antioxidant enzymes glutathione peroxidase by 17.8 % (P < 0.01), superoxide dismutase by 11.8 % (P < 0.05) and glutathione-S-transferase by 25.3 % (P < 0.01). The increased antioxidant activity measured by different methods was found -FRAP method showed an increase by 17.8 % (P < 0.05), FR by 20.3 % (P < 0.05), and ABTS by 12.4 % (P < 0.05). Reduced form of glutathione was increased by 33.1 % (P < 0.001). Concentration of selenium was increased by 55.2 % (P < 0.001). Content of cadmium was significantly reduced (by 12.8 % (P < 0.05)), on the other hand, content of copper was significantly increased (by 29.5 % (P < 0.001)) in comparison with control group of animals. The obtained results show that the addition of selenium in a dose of 0.30 and 0.55 mg/kg FM increased antioxidant status in postpartum sows. The results may show possible beneficial effect of selenium on health status in postpartum sows.

Keywords

Selenium; Antioxidant Status; Erythrocytes; Sows; Electrochemical Detection

Authors

HORKÝ, P.; RUTTKAY-NEDECKÝ, B.; KREMPLOVÁ, M.; KRYŠTOFOVÁ, O.; KENŠOVÁ, R.; HYNEK, D.; BABULA, P.; ZÍTKA, O.; ZEMAN, L.; ADAM, V.; KIZEK, R.

Released

1. 5. 2013

ISBN

1452-3981

Periodical

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE

Year of study

8

Number

5

State

Republic of Serbia

Pages from

6162

Pages to

6179

Pages count

18

BibTex

@article{BUT142308,
  author="Pavel {Horký} and Branislav {Ruttkay-Nedecký} and Monika {Kremplová} and Olga {Kryštofová} and Renáta {Kenšová} and David {Hynek} and Petr {Babula} and Ondřej {Zítka} and Ladislav {Zeman} and Vojtěch {Adam} and René {Kizek}",
  title="Effect of Different Doses of Organically Bound Selenium on Antioxidant Status and Levels of Metal Ions in Postpartum Sows",
  journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE",
  year="2013",
  volume="8",
  number="5",
  pages="6162--6179",
  issn="1452-3981"
}