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KŘÍŽOVÁ, A. BALVAN, J. GUMULEC, J. SLABÝ, T. MASAŘÍK, M. CHMELÍK, R.
Original Title
Cell death type identification by quantitative phase imaging
Type
abstract
Language
English
Original Abstract
Exact identification of cell death type is important for instance in diagnostics, dose-response, and toxicological studies. Predominant types of cell death are usually detected by flow-cytometry (FCM), where the absence of the analysis of cellular morphology leads to the misclassification of cell death type due to underestimated oncosis. The definition of oncosis is important because of its potential reversibility. Therefore, FCM analysis of cell death using the annexin V/propidium iodide assay was compared with quantitative phase imaging (QPI) coupled with fluorescence detection.
Keywords
Cell death type identification
Authors
KŘÍŽOVÁ, A.; BALVAN, J.; GUMULEC, J.; SLABÝ, T.; MASAŘÍK, M.; CHMELÍK, R.
Released
15. 4. 2015
ISBN
1059-1524
Periodical
MOLECULAR BIOLOGY OF THE CELL
Year of study
26
State
United States of America
Pages from
P1553
Pages count
1