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KREJČOVÁ, L. HYNEK, D. KOPEL, P. ADAM, V. KIZEK, R.
Original Title
3D CHIP AS A TOOL FOR ISOLATION AND DETECTION OF INFLUENZA VACCINE HEMAGGLUTININ
Type
conference paper
Language
English
Original Abstract
The aim of this study was an isolation and detection of influenza antigen using 3D fabricated chip. Surface of influenza virion is equipped with two antigens: hemagglutinin (HA) and neuraminidase (NA), which are responsible for virus life cycle and interaction with host cell. In this study, vaccine HA, labeled by quantum dots (QDs) was used for better specification. The 3D chip assay was divided in two parts: paramagnetic particles (MPs) based isolation and electrochemical detection of isolated product. Our results show, that 3D fabricated chip is useable tool for MPs based isolation and electrochemical detection influenza hemagglutinin.
Keywords
3D chip; voltammetry; influenza; hemagglutinin; quantum dots; paramagnetic particles
Authors
KREJČOVÁ, L.; HYNEK, D.; KOPEL, P.; ADAM, V.; KIZEK, R.
Released
21. 11. 2013
ISBN
978-80-7375-908-7
Book
MENDELNET 2013
Pages from
753
Pages to
757
Pages count
5
BibTex
@inproceedings{BUT142536, author="Ludmila {Krejčová} and David {Hynek} and Pavel {Kopel} and Vojtěch {Adam} and René {Kizek}", title="3D CHIP AS A TOOL FOR ISOLATION AND DETECTION OF INFLUENZA VACCINE HEMAGGLUTININ", booktitle="MENDELNET 2013", year="2013", pages="753--757", isbn="978-80-7375-908-7" }