Publication detail

PREPARATION AND ANTIMICROBIAL ACTIVITY OF NUCLEOBASE-CONJUGATED CdTe / ZnSe CORE / SHELL QUANTUM DOTS

MOULICK, A. ČÍHALOVÁ, K. MILOSAVLJEVIĆ, V. KOPEL, P. ADAM, V. HEGER, Z. KIZEK, R.

Original Title

PREPARATION AND ANTIMICROBIAL ACTIVITY OF NUCLEOBASE-CONJUGATED CdTe / ZnSe CORE / SHELL QUANTUM DOTS

Type

conference paper

Language

English

Original Abstract

Inorganic nanomaterials have large specific surface area and high bioactivity which made them promising alternatives to the traditional organic antimicrobial agents that are extremely irritant and toxic. In the present report, CdTe/ZnSe core/shell quantum dots (QDs) were conjugated with different nucleobases and their antibacterial activity against Escherichia coli was investigated. The CdTe/ZnSe core/shell QDs were synthesized in a green way or environment-friendly way using water as a solvent instead of organic solvents. They were successfully conjugated with different nucleobases and were characterized using fluorescence and absorbance spectrophotometry and dynamic light scattering techniques. The antimicrobial activity of all the samples along with control (bare QDs) was checked on E. coli, a commonly used bacterial model species in microbiology research. Almost all nucleobases showed good antibacterial activity comparing to control probably forming excess ROS which can disturb different metabolisms in bacterial cell. Guanine showed the best result among all other nucleobases.

Keywords

Quantum dots; nucleobases; antibacterial activity

Authors

MOULICK, A.; ČÍHALOVÁ, K.; MILOSAVLJEVIĆ, V.; KOPEL, P.; ADAM, V.; HEGER, Z.; KIZEK, R.

Released

16. 10. 2015

ISBN

978-80-87294-63-5

Book

NANOCON 2015

Pages from

537

Pages to

541

Pages count

5

BibTex

@inproceedings{BUT143521,
  author="Amitava {Moulick} and Kristýna {Číhalová} and Vedran {Milosavljević} and Pavel {Kopel} and Vojtěch {Adam} and Zbyněk {Heger} and René {Kizek}",
  title="PREPARATION AND ANTIMICROBIAL ACTIVITY OF NUCLEOBASE-CONJUGATED CdTe / ZnSe CORE / SHELL QUANTUM DOTS",
  booktitle="NANOCON 2015",
  year="2015",
  pages="537--541",
  isbn="978-80-87294-63-5"
}