Publication detail

Microfluidic device based on deep reactive ion etching process and its lag effect for single cell capture and extraction

FENG, J. FOHLEROVÁ, Z. LIU, X. CHANG, H. NEUŽIL, P.

Original Title

Microfluidic device based on deep reactive ion etching process and its lag effect for single cell capture and extraction

Type

journal article in Web of Science

Language

English

Original Abstract

We introduced a microfluidic device for high-efficiency single cell capture and their subsequent extraction. It was fabricated by using a deep reactive ion etching process taking advantage of the lag effect. We accomplished single cell capture based on the least flow resistance path principle as well as independent extraction of individual captured cells to perform their subsequent analysis. The device was performed with >99% single cell capture efficiency.

Keywords

microfluidic device; single cell capture and extraction; deep reactive ion etching; lag effect; the least flow resistance path

Authors

FENG, J.; FOHLEROVÁ, Z.; LIU, X.; CHANG, H.; NEUŽIL, P.

Released

15. 9. 2018

Publisher

Elsevier

ISBN

0925-4005

Periodical

Sensors and Actuators B: Chemical

Year of study

269

Number

1

State

Swiss Confederation

Pages from

288

Pages to

292

Pages count

5

URL

https://www.sciencedirect.com/science/article/pii/S0925400518308931#ack0005

BibTex

@article{BUT147244,
  author="Jianguo {Feng} and Zdenka {Fohlerová} and Xiaocheng {Liu} and Honglong {Chang} and Pavel {Neužil}",
  title="Microfluidic device based on deep reactive ion etching process and its lag effect for single cell capture and extraction",
  journal="Sensors and Actuators B: Chemical",
  year="2018",
  volume="269",
  number="1",
  pages="288--292",
  doi="10.1016/j.snb.2018.04.179",
  issn="0925-4005",
  url="https://www.sciencedirect.com/science/article/pii/S0925400518308931#ack0005"
}