Publication detail

Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity

ŠŤASTNÝ, P. TRUNEC, M. MAN, O. LUKÁŠOVÁ, V. SEDLÁČEK, R.

Original Title

Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity

Type

abstract

Language

English

Original Abstract

Resorbable porous ceramic materials with customized shape are promising category of materials for healing of bone defects with critical size1. Resorption rate of the ceramic structure must correspond to the bone tissue regeneration. The only mechanism of degradation of sintered ceramic materials in a human body is via dissolution under acidic conditions produced by osteoclastic cells2. Dissolution of the ceramics correspond to changes in its mechanical strength. In our research we described structural and mechanical changes of different types of calcium phosphate ceramic materials under acidic conditions simulating osteoclastic activity. Results will help to develop bioceramic scaffolds with controlled resorption rate with good mechanical strength during healing period.

Keywords

biodegradation, calcium phosphates

Authors

ŠŤASTNÝ, P.; TRUNEC, M.; MAN, O.; LUKÁŠOVÁ, V.; SEDLÁČEK, R.

Released

9. 9. 2018

Pages from

625

Pages to

625

Pages count

1099

URL

http://www.esb2018maastricht.org/resources/media/Programme/ESB_2018_Abstract__Proceedings_4.pdf

BibTex

@misc{BUT150763,
  author="Přemysl {Šťastný} and Martin {Trunec} and Ondřej {Man} and Věra {Lukášová} and Radek {Sedláček}",
  title="Strength degradation, phase and morphological changes of calcium phosphate scaffolds in acidic environment simulating osteoclastic activity",
  year="2018",
  pages="625--625",
  url="http://www.esb2018maastricht.org/resources/media/Programme/ESB_2018_Abstract__Proceedings_4.pdf",
  note="abstract"
}