Publication detail

Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina

TORNOW, R. ODSTRČILÍK, J. KOLÁŘ, R.

Original Title

Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina

Type

journal article in Web of Science

Language

English

Original Abstract

We describe a low-cost, easy to use binocular instrument to acquire retinal video sequences of both eyes simultaneously. After image registration, cardiac cycle-induced pulsatile light attenuation changes can be measured quantitatively with high spatial and temporal resolution. Parameters such as amplitude, pulse form, and time shift between light attenuation changes can be calculated and compared between eye sides. Deviation from inter-eye symmetry can be not only an early sign of beginning eye diseases such as glaucoma but also a sign of pathological changes in the carotid arteries; hence, this method can improve the early detection of pathological changes. Important features compared to existing monocular instruments are a narrow band light source with the wavelength close to the peak of the blood extinction, and a proportional relationship of image intensity and light intensity, which are the main requirements for quantitative evaluation.

Keywords

retinal imaging, perfusion, photoplethysmography, image processing

Authors

TORNOW, R.; ODSTRČILÍK, J.; KOLÁŘ, R.

Released

14. 11. 2018

Publisher

Optical Society of America

Location

USA

ISBN

2156-7085

Periodical

Biomedical Optics Express

Year of study

9

Number

12

State

United States of America

Pages from

6237

Pages to

6254

Pages count

18

URL

https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-12-6237

BibTex

@article{BUT151242,
  author="Ralf-Peter {Tornow} and Jan {Odstrčilík} and Radim {Kolář}",
  title="Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina",
  journal="Biomedical Optics Express",
  year="2018",
  volume="9",
  number="12",
  pages="6237--6254",
  doi="10.1364/BOE.9.006237",
  issn="2156-7085",
  url="https://www.osapublishing.org/boe/abstract.cfm?uri=boe-9-12-6237"
}