Publication detail

Capillary gap flow cell as capillary-end electrochemical detector in flow-based analysis

ISLAM, M. LAM, S. LI, Y. ATIA, M. MAHBUB, P. NESTERENKO, P. PAULL, B. MACKA, M.

Original Title

Capillary gap flow cell as capillary-end electrochemical detector in flow-based analysis

Type

journal article in Web of Science

Language

English

Original Abstract

A gap flow cell (gap-FC) as a capillary-end electrochemical (EC) detector, incorporating exchangeable screen-printed electrodes, that facilitates adjustment of the gap distance between the capillary outlet and working electrode down to 30 um was investigated. The analytical performance of the gap-FC was assessed in terms of detector response (current), the efficiency of EC conversion of ferrocyanide, and effective cell volume, as a function of flow rate and gap distance, within a range of 0.1-200 mu L min(-1) and 30-100 mu m, respectively. As a result, an efficiency of EC conversion within the range of similar to 1.5-11% (similar to 3-16 times higher than wall-jet FC), at an effective cell volume of similar to 30-75 nL, was achieved. The gap-FC was applied as a liquid chromatography EC detector, coupled with standard and capillary format liquid chromatographs, where the analytical performance of gap-FC was compared with that of a UV detector. With the standard LC, the sensitivity for ascorbic acid, 2,3-dihydroxybenzoic acid and pyrocatechol, was greater than with the UV detector, with limits of detection (LODs) one order of magnitude lower for the gap-FC (0.10 mu M, 0.09 mu M, 0.19 mu M, respectively, RSD 1.35-3.8%, n = 9, linearity r(2) similar to 0.99 for concentration range 1-100 mu M). LODs of test electroactive solutes using the gap-FC were similar to 2 times lower than LODs reported in existing literature using standard EC detectors, including wall-jet and thin-layer FCs.

Keywords

Conversion efficiency; Effective cell volume; Flow-based analysis; Gap distance; Gap flow cell

Authors

ISLAM, M.; LAM, S.; LI, Y.; ATIA, M.; MAHBUB, P.; NESTERENKO, P.; PAULL, B.; MACKA, M.

Released

20. 4. 2019

ISBN

0013-4686

Periodical

Electrochimica Acta

Year of study

303

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

85

Pages to

93

Pages count

9

BibTex

@article{BUT156535,
  author="Muhammed Ariful {Islam} and Shing Chung {Lam} and Yan {Li} and Mostafa A. {Atia} and Parvez {Mahbub} and Pavel {Nesterenko} and Brett {Paull} and Miroslav {Macka}",
  title="Capillary gap flow cell as capillary-end electrochemical detector in flow-based analysis",
  journal="Electrochimica Acta",
  year="2019",
  volume="303",
  number="1",
  pages="85--93",
  doi="10.1016/j.electacta.2019.02.026",
  issn="0013-4686"
}