Publication detail

Microfluidic Technology for Clinical Applications of Exosomes

ILIESCU, F. VRTAČNIK, D. NEUŽIL, P. ILIESCU, C.

Original Title

Microfluidic Technology for Clinical Applications of Exosomes

Type

journal article in Web of Science

Language

English

Original Abstract

Exosomes, a type of nanovesicle, are distinct cellular entities specifically capable of carrying various cargos between cells. It has been hypothesized that exosomes, as an enriched source of biomolecules, may serve as biomarkers for various diseases. This review introduces general aspects of exosomes, presents the challenges in exosome research, discusses the potential of exosomes as biomarkers, and describes the contribution of microfluidic technology to enable their isolation and analysis for diagnostic and disease monitoring. Additionally, clinical applications of exosomes for diagnostic purposes are also summarized.

Keywords

microfluidics; exosomes; clinical applications; extracellular vesicles; cancer; inflammation

Authors

ILIESCU, F.; VRTAČNIK, D.; NEUŽIL, P.; ILIESCU, C.

Released

12. 6. 2019

Publisher

MDPI

Location

BASEL, SWITZERLAND

ISBN

2072-666X

Periodical

Micromachines

Year of study

10

Number

6

State

Swiss Confederation

Pages from

1

Pages to

29

Pages count

29

URL

https://www.mdpi.com/2072-666X/10/6/392

Full text in the Digital Library

http://hdl.handle.net/11012/184662

BibTex

@article{BUT159955,
  author="Florina Silvia {Iliescu} and Danilo {Vrtačnik} and Pavel {Neužil} and Ciprian {Iliescu}",
  title="Microfluidic Technology for Clinical Applications of Exosomes",
  journal="Micromachines",
  year="2019",
  volume="10",
  number="6",
  pages="1--29",
  doi="10.3390/mi10060392",
  issn="2072-666X",
  url="https://www.mdpi.com/2072-666X/10/6/392"
}