Publication detail

Lubricating ability of albumin and globulin on artificial joint implants: a tribological perspective

Ghosh, S. Choudhury, D. Pingguan-Murphy, B.

Original Title

Lubricating ability of albumin and globulin on artificial joint implants: a tribological perspective

Type

journal article in Web of Science

Language

English

Original Abstract

Albumin and globulin proteins are dominant protein components in synovial fluid, and play important roles in the lubrication mechanism of joint prostheses. The present study investigated the lubricating ability of albumin and globulin on ceramic-on-polyethylene joint implants. A pin-on-disk tribometer was used for friction tests where the experimental condition was replicated with a simulated hip joint condition. The experiment was conducted under three lubricating conditions: bovine synovial fluid (BSF), albumin and globulin. Mechanical properties of specimens and physical properties of lubricant were measured before and after the tests. The experimental results show that albumin yielded a lower friction coefficient as compared to globulin. However, both exhibited a higher friction coefficient and wear rate than that of bovine synovial fluid. This study suggests that further tribological investigations on major biological components of synovial fluid should be carried out, which will help optimise implant design.

Keywords

albumin; globulin; friction; wear; tribology

Authors

Ghosh, S.; Choudhury, D.; Pingguan-Murphy, B.

Released

1. 1. 2016

Publisher

INDERSCIENCE ENTERPRISES LTD

Location

GENEVA

ISBN

1749-7868

Periodical

INTERNATIONAL JOURNAL OF SURFACE SCIENCE AND ENGINEERING

Year of study

10

Number

2

State

United Kingdom of Great Britain and Northern Ireland

Pages from

193

Pages to

206

Pages count

14

URL

https://www.inderscience.com/info/inarticle.php?artid=76516

BibTex

@article{BUT163333,
  author="Ghosh, S. and Choudhury, D. and Pingguan-Murphy, B.",
  title="Lubricating ability of albumin and globulin on artificial joint implants: a tribological perspective",
  journal="INTERNATIONAL JOURNAL OF SURFACE SCIENCE AND ENGINEERING",
  year="2016",
  volume="10",
  number="2",
  pages="193--206",
  doi="10.1504/IJSURFSE.2016.076516",
  issn="1749-7868",
  url="https://www.inderscience.com/info/inarticle.php?artid=76516"
}