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MAYORGA-MARTINEZ, C. PUMERA, M.
Original Title
Self-Propelled Tags for Protein Detection
Type
journal article in Web of Science
Language
English
Original Abstract
Protein detection is of tremendous significance for biological and biomedical sciences. Because there is no equivalent of polymerase chain reaction available as a tool for protein detection, researchers must rely on tags to enhance the limits of detection. One of the crucial steps is the actual labeling of proteins, which relies on diffusion of the label, which is very slow, or external mixing of the label and protein is needed. Here, a conceptually new approach is demonstrated: self-propelled tags that autonomously move in the solution and enhance protein detection. The tags used here are based on IrO2/Pt bilayer microtubules, which can self-propel and act as moving tags for enhanced protein electrochemical detection. This completely new label-based protein detection concept using self-propelled tag will find a wide spectrum of applications.
Keywords
bubble propulsion; hydrogen evolution reaction; label-based protein detection; magneto-immunoassay; micromotor; transitional metal oxides
Authors
MAYORGA-MARTINEZ, C.; PUMERA, M.
Released
1. 2. 2020
Publisher
WILEY-V C H VERLAG GMBH
Location
WEINHEIM
ISBN
1616-301X
Periodical
ADVANCED FUNCTIONAL MATERIALS
Year of study
30
Number
6
State
Federal Republic of Germany
Pages from
1
Pages to
7
Pages count
URL
https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201906449
BibTex
@article{BUT163848, author="Carmen C. {Mayorga-Martinez} and Martin {Pumera}", title="Self-Propelled Tags for Protein Detection", journal="ADVANCED FUNCTIONAL MATERIALS", year="2020", volume="30", number="6", pages="1--7", doi="10.1002/adfm.201906449", issn="1616-301X", url="https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201906449" }