Publication detail

Nanomaterials with active targeting as advanced antimicrobials

ŠMERKOVÁ, K. DOLEŽELÍKOVÁ, K. BOZDĚCHOVÁ, L. HEGER, Z. ŽŮREK, L. ADAM, V.

Original Title

Nanomaterials with active targeting as advanced antimicrobials

Type

journal article in Web of Science

Language

English

Original Abstract

With a growing health threat of bacterial resistance to antibiotics, the nanomaterials have been extensively studied as an alternative. It is assumed that antimicrobial nanomaterials can affect bacteria by several mechanisms simultaneously and thereby overcome antibiotic resistance. Another promising potential use is employing nanomaterials as nanocarriers for antibiotics in order to overcome bacterial defense mechanisms. The passive targeting of nanomaterials is the often used strategy for bacterial treatment, including intracellular infections of macrophages. Furthermore, the specific targeting enhances the efficacy of antimicrobials and reduces side effects. This review aims to discuss advantages, disadvantages, and challenges of nanomaterials in the context of the targeting strategies for antimicrobials as advanced tools for treatments of bacterial infections.

Keywords

biomimetic; delivery; nanomedicine; peptide; resistance

Authors

ŠMERKOVÁ, K.; DOLEŽELÍKOVÁ, K.; BOZDĚCHOVÁ, L.; HEGER, Z.; ŽŮREK, L.; ADAM, V.

Released

25. 5. 2020

ISBN

1939-5116

Periodical

WIRES NANOMED NANOBI

Number

e1636

State

United States of America

Pages from

1

Pages to

25

Pages count

25

URL

https://doi.org/10.1002/wnan.1636

BibTex

@article{BUT164053,
  author="Kristýna {Šmerková} and Kristýna {Doleželíková} and Lucie {Bozděchová} and Zbyněk {Heger} and Luděk {Žůrek} and Vojtěch {Adam}",
  title="Nanomaterials with active targeting as advanced antimicrobials",
  journal="WIRES NANOMED NANOBI",
  year="2020",
  number="e1636",
  pages="1--25",
  doi="10.1002/wnan.1636",
  issn="1939-5116",
  url="https://doi.org/10.1002/wnan.1636"
}