Přístupnostní navigace
E-application
Search Search Close
Publication detail
DZURICKÁ, L. BENDOVÁ, A. HOOVÁ, J. MATOUŠKOVÁ, P. MÁROVÁ, I.
Original Title
Preparation and characterisation of functionalized wound dressings
Type
abstract
Language
English
Original Abstract
This work is focused on preparation and characterization of bio-active hydrogels and nanofiber wound dressings functionalized by active compound in the form of antibiotic drug: ampicillin. Nano-fiber dressings were constituted from poly(3-hydroxybutyrate) and hydrogel dressings were created using alginate and chitosan. Prepared wound dressings were tested for possible cytotoxic ef-fects on human cells, antimicrobial activity and the rate of gradual releasing of the incorporated substance into model environments.Nanofibers were assembled by electrospinning and force spin-ning techniques. Morphology of the prepared nanofibers was con-firmed by SEM. Dressings were characterized for gradual release using spectrophotometric methods. Antimicrobial activity against gram-positive and gram-negative strains of microorganisms was also evaluated. the results showed good antimicrobial efficacy of functionalized materials.
Keywords
wound dressings, ampicillin, poly(3‑hydroxybutyrate), chitosan, alginate, antimicrobial activity, cytotoxicity
Authors
DZURICKÁ, L.; BENDOVÁ, A.; HOOVÁ, J.; MATOUŠKOVÁ, P.; MÁROVÁ, I.
Released
26. 11. 2020
Publisher
Vysoké učení technické v Brně, Fakulta chemická
Location
Brno
ISBN
978-80-214-5920-0
Book
Studentská odborná konference CHEMIE JE ŽIVOT 2020 Sborník abstraktů
Edition number
první
Pages from
59
Pages to
60
Pages count
164
URL
https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstrakty-konference-2020-pdf-p198641
BibTex
@misc{BUT166180, author="Lucia {Dzurická} and Agáta {Bendová} and Julie {Hoová} and Petra {Skoumalová} and Ivana {Márová}", title="Preparation and characterisation of functionalized wound dressings", booktitle="Studentská odborná konference CHEMIE JE ŽIVOT 2020 Sborník abstraktů", year="2020", edition="první", pages="59--60", publisher="Vysoké učení technické v Brně, Fakulta chemická", address="Brno", isbn="978-80-214-5920-0", url="https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstrakty-konference-2020-pdf-p198641", note="abstract" }