Publication detail

Arsenene nanomotors as anticancer drug carrier

ROSLI, N. MAYORGA-MARTINEZ, C. FISHER, A. ALDUHAISH, O. WEBSTER, R. PUMERA, M.

Original Title

Arsenene nanomotors as anticancer drug carrier

Type

journal article in Web of Science

Language

English

Original Abstract

Nanotechnology has allowed rapid advancements in nanomachines for variety of biomedical applications, including drug delivery, due to their loading and transporting capabilities. Utilizing pnictogen, such as arsenic, antimony and bismuth, as nanomachines for biomedical applications are still in infancy. Herein, template-less arsenene-based Janus nanomachines with layered structure which allowed high loading capacity are explored by specifically modifying arsenene nanoparticles with platinum, forming As-Pt nanomotors. Their motion capabilities, biocompatibility and drug loading competency were thoroughly investigated. The results showed fast, biocompatible, high drug loading and high cellular uptake of As-Pt nanomotors. These findings open new direction in arsenene nanoparticles as nontoxic self-propelled drug carrier applications. (C) 2020 Elsevier Ltd. All rights reserved.

Keywords

Pnictogen; Nanomaterials; Doxorubicin; Toxicity; Micromotors

Authors

ROSLI, N.; MAYORGA-MARTINEZ, C.; FISHER, A.; ALDUHAISH, O.; WEBSTER, R.; PUMERA, M.

Released

1. 12. 2020

Publisher

ELSEVIER

Location

AMSTERDAM

ISBN

2352-9407

Periodical

Applied Materials Today

Year of study

21

Number

1

State

Kingdom of the Netherlands

Pages from

100819-1

Pages to

100819-8

Pages count

8

URL

https://www.sciencedirect.com/science/article/pii/S2352940720302675