Publication detail

Graphene oxide as a nanocarrier for biochemical molecules: Current understanding and trends

MUKHERJEE, S. BYTEŠNÍKOVÁ, Z. AMIRMANSOOR, A. ADAM, V. RICHTERA, L.

Original Title

Graphene oxide as a nanocarrier for biochemical molecules: Current understanding and trends

Type

journal article in Web of Science

Language

English

Original Abstract

The development of an advanced and efficient drug delivery system with significant improvement in its efficacy and enhanced therapeutic value is one of the critical challenges in modern medicinal biology. The integration of nanomaterial science with molecular and cellular biology has helped in the advancement and development of novel drug delivery nanocarrier systems with precision and decreased side effects. The design and synthesis of nanocarriers using graphene oxide (GO) have been rapidly growing over the past few years. Due to its remarkable physicochemical properties, GO has been extensively used in efforts to construct nanocarriers with high specificity, selectivity, and biocompatibility, and low cytotoxicity. The focus of this review is to summarize and address recent uses of GO-based nanocarriers and the improvements as efficient drug delivery systems. We briefly describe the concepts and challenges associated with nanocarrier systems followed by providing critical examples of GO-based delivery of drug molecules and genes. Finally, the review delivers brief conclusions on the current understanding and prospects of nanocarrier delivery systems.

Keywords

graphene oxide; graphene; nanocarrier; drug delivery; nanomaterials; cancer drug; gene delivery

Authors

MUKHERJEE, S.; BYTEŠNÍKOVÁ, Z.; AMIRMANSOOR, A.; ADAM, V.; RICHTERA, L.

Released

30. 12. 2020

Publisher

MDPI

ISBN

2227-9717

Periodical

Processes

Year of study

8

Number

12

State

Swiss Confederation

Pages from

1

Pages to

22

Pages count

22

URL

https://www.mdpi.com/2227-9717/8/12/1636

Full text in the Digital Library

http://hdl.handle.net/11012/195919

BibTex

@article{BUT168305,
  author="S. {Mukherjee} and Zuzana {Bytešníková} and Amirmansoor {Ashrafi} and Vojtěch {Adam} and Lukáš {Richtera}",
  title="Graphene oxide as a nanocarrier for biochemical molecules: Current understanding and trends",
  journal="Processes",
  year="2020",
  volume="8",
  number="12",
  pages="1--22",
  doi="10.3390/pr8121636",
  issn="2227-9717",
  url="https://www.mdpi.com/2227-9717/8/12/1636"
}