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CHYRÁ, Z. ŠEVČÍKOVÁ, T. VOJTA, P. PUTEROVÁ, J. BROŽOVÁ, L. GROWKOVÁ, K. FILIPOVÁ, J. ZÁTOPKOVÁ, M. GROSICKI, S. BARCHANICKA, A. JĘDRZEJCZAK, W. WASZCZUK-GAJDA, A. JUNGOVÁ, A. MIKULÁŠOVÁ, A. HAJDÚCH, M. MOKREJŠ, M. POUR, L. ŠTORK, M. HARVANOVÁ, Ľ. MISTRÍK, M. MIKALA, G. ROBAK, P. CZYŻ, A. DĘBSKI, J. USNARSKA-ZUBKIEWICZ, L. JURCZYSZYN, A. STEJSKAL, L. MORGAN, G. KRYUKOV, F. BUDINSKÁ, E. ŠIMÍČEK, M. JELÍNEK, T. HRDINKA, M. HÁJEK, R.
Original Title
Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis
Type
journal article in Web of Science
Language
English
Original Abstract
We aim to provide the very first insight into ALA (amyloidosis) +MM (multiple myeloma) molecular profiles and compare the results with ALA and with MM. Our detailed study of ALA and ALA+MM represents an important step towards the improved understanding of their genetic and transcriptomic background, which is a prerequisite for the development of optimal treatment strategies in the future.
Keywords
amyloidosis, multiple myeloma, clonality, cancer
Authors
CHYRÁ, Z.; ŠEVČÍKOVÁ, T.; VOJTA, P.; PUTEROVÁ, J.; BROŽOVÁ, L.; GROWKOVÁ, K.; FILIPOVÁ, J.; ZÁTOPKOVÁ, M.; GROSICKI, S.; BARCHANICKA, A.; JĘDRZEJCZAK, W.; WASZCZUK-GAJDA, A.; JUNGOVÁ, A.; MIKULÁŠOVÁ, A.; HAJDÚCH, M.; MOKREJŠ, M.; POUR, L.; ŠTORK, M.; HARVANOVÁ, Ľ.; MISTRÍK, M.; MIKALA, G.; ROBAK, P.; CZYŻ, A.; DĘBSKI, J.; USNARSKA-ZUBKIEWICZ, L.; JURCZYSZYN, A.; STEJSKAL, L.; MORGAN, G.; KRYUKOV, F.; BUDINSKÁ, E.; ŠIMÍČEK, M.; JELÍNEK, T.; HRDINKA, M.; HÁJEK, R.
Released
6. 2. 2021
ISBN
1592-8721
Periodical
Haematologica
Year of study
106
Number
2
State
Republic of Italy
Pages from
601
Pages to
604
Pages count
4
URL
https://haematologica.org/article/view/9744
BibTex
@article{BUT168529, author="CHYRÁ, Z. and ŠEVČÍKOVÁ, T. and VOJTA, P. and PUTEROVÁ, J. and BROŽOVÁ, L. and GROWKOVÁ, K. and FILIPOVÁ, J. and ZÁTOPKOVÁ, M. and GROSICKI, S. and BARCHANICKA, A. and JĘDRZEJCZAK, W. and WASZCZUK-GAJDA, A. and JUNGOVÁ, A. and MIKULÁŠOVÁ, A. and HAJDÚCH, M. and MOKREJŠ, M. and POUR, L. and ŠTORK, M. and HARVANOVÁ, Ľ. and MISTRÍK, M. and MIKALA, G. and ROBAK, P. and CZYŻ, A. and DĘBSKI, J. and USNARSKA-ZUBKIEWICZ, L. and JURCZYSZYN, A. and STEJSKAL, L. and MORGAN, G. and KRYUKOV, F. and BUDINSKÁ, E. and ŠIMÍČEK, M. and JELÍNEK, T. and HRDINKA, M. and HÁJEK, R.", title="Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis", journal="Haematologica", year="2021", volume="106", number="2", pages="601--604", doi="10.3324/haematol.2019.239756", issn="1592-8721", url="https://haematologica.org/article/view/9744" }