Publication detail

Towards nanoparticle mediated biomolecule delivery: effect of gold and PEI-capped gold nanoparticles on viability and growth in Chlamydomonas reinhardtii

CHALOUPSKÝ, P. SEDLÁČKOVÁ, E. DVOŘÁK, M. BAŘINKOVÁ, M. HÚSKA, D.

Original Title

Towards nanoparticle mediated biomolecule delivery: effect of gold and PEI-capped gold nanoparticles on viability and growth in Chlamydomonas reinhardtii

Type

conference paper

Language

English

Original Abstract

Unicellular algae are promising organisms potentially suitable for plethora of biotechnological applications. However, currently utilized methods of biomolecule delivery are limiting factor for broader utilization of the microalgae in genetic and metabolomic engineering. Currently utilized methods are often inefficient and result in cellular damage with accompanying difficulties with consequent regeneration. In order to overcome the barrier of the cell wall and membrane, nanomaterials can be employed in order to deliver molecular cargo. Within this study, we evaluated influence of different Au nanomaterials with and without surface modifications on viability and growth in order to select suitable material for delivery of genetic material into the unicellular alga Ch. reinhardtii.

Keywords

nanocariers; surface modifications; molecular cargo; toxicity

Authors

CHALOUPSKÝ, P.; SEDLÁČKOVÁ, E.; DVOŘÁK, M.; BAŘINKOVÁ, M.; HÚSKA, D.

Released

7. 11. 2019

ISBN

978-80-7509-688-3

Book

MendelNet 2019: Proceedings of International PhD Students Conference

Pages from

414

Pages to

418

Pages count

5

URL

https://mnet.mendelu.cz/mendelnet2019/mnet_2019_full.pdf

BibTex

@inproceedings{BUT170487,
  author="Pavel {Chaloupský} and Eliška {Dostálová} and Marek {Dvořák} and Magda {Bařinková} and Dalibor {Húska}",
  title="Towards nanoparticle mediated biomolecule delivery: effect of gold and PEI-capped gold nanoparticles on viability and growth in Chlamydomonas reinhardtii",
  booktitle="MendelNet 2019: Proceedings of International PhD Students Conference",
  year="2019",
  pages="414--418",
  isbn="978-80-7509-688-3",
  url="https://mnet.mendelu.cz/mendelnet2019/mnet_2019_full.pdf"
}