Publication detail

The underexplored role of diverse stress factors in microbial biopolymer synthesis

OBRUČA, S. SEDLÁČEK, P. KOLLER, M.

Original Title

The underexplored role of diverse stress factors in microbial biopolymer synthesis

Type

journal article in Web of Science

Language

English

Original Abstract

Polyhydroxyalkanoates (PHA) are microbial polyesters which, apart from their primary storage role, enhance the stress robustness of PHA accumulating cells against various stressors. PHA also represent interesting alternatives to petrochemical polymers, which can be produced from renewable resources employing approaches of microbial biotechnology. During biotechnological processes, bacterial cells are exposed to various stressor factors such as fluctuations in temperature, osmolarity, pH-value, elevated pressure or the presence of microbial inhibitors. This review summarizes how PHA helps microbial cells to cope with biotechnological process-relevant stressors and, vice versa, how various stress conditions can affect PHA production processes. The review suggests a fundamentally new strategy for PHA production: the fine-tuned exposure to selected stressors, which might be used to boost PHA production and even to tailor their structure.

Keywords

Biotechnological process; Hormesis; Polyhydroxyalkanoates; Stress conditions; Waste substrates

Authors

OBRUČA, S.; SEDLÁČEK, P.; KOLLER, M.

Released

1. 4. 2021

Publisher

ELSEVIER SCI LTD

Location

Oxford

ISBN

0960-8524

Periodical

BIORESOURCE TECHNOLOGY

Year of study

326

Number

4

State

Kingdom of the Netherlands

Pages from

1

Pages to

12

Pages count

12

URL

https://www.sciencedirect.com/science/article/pii/S0960852421001061

BibTex

@article{BUT170832,
  author="Stanislav {Obruča} and Petr {Sedláček} and Martin {Koller}",
  title="The underexplored role of diverse stress factors in microbial biopolymer synthesis",
  journal="BIORESOURCE TECHNOLOGY",
  year="2021",
  volume="326",
  number="4",
  pages="1--12",
  doi="10.1016/j.biortech.2021.124767",
  issn="0960-8524",
  url="https://www.sciencedirect.com/science/article/pii/S0960852421001061"
}