Publication detail

COVID-19: A challenge for electrochemical biosensors

KUDR, J. MICHÁLEK, P. ILIEVA, L. ADAM, V. ZÍTKA, O.

Original Title

COVID-19: A challenge for electrochemical biosensors

Type

journal article in Web of Science

Language

English

Original Abstract

Coronavirus disease (COVID-19) caused by SARS-CoV-2 has spread since the end of 2019 and has resulted in a pandemic with unprecedented socioeconomic consequences. This situation has created enormous demand for the improvement of current diagnostic methods and the development of new diagnostic methods for fast, low-cost and user-friendly confirmation of SARS-CoV-2 infection. This critical review focuses on viral electrochemical biosensors that are promising for the development of rapid medical COVID-19 diagnostic tools. The molecular biological properties of SARS-CoV-2 as well as currently known biochemical attributes of infection necessary for biosensor development are outlined. The advantages and drawbacks of conventional diagnostic methods, such as quantitative reverse-transcription polymerase chain reaction (qRT-PCR), are critically discussed. Electrochemical biosensors focusing on viral nucleic acid and whole viral particle detection are highlighted and discussed in detail. Finally, future perspectives on viral electrochemical biosensor development are briefly mentioned.

Keywords

Antibody; CRISPR; Cas9; Diagnostics; Electrochemistry; Electrode

Authors

KUDR, J.; MICHÁLEK, P.; ILIEVA, L.; ADAM, V.; ZÍTKA, O.

Released

1. 3. 2021

ISBN

0165-9936

Periodical

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Year of study

136

Number

116192

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

9

Pages count

9

URL

https://doi.org/10.1016/j.trac.2021.116192

BibTex

@article{BUT171292,
  author="Jiří {Kudr} and Petr {Michálek} and Lada {Ilieva} and Vojtěch {Adam} and Ondřej {Zítka}",
  title="COVID-19: A challenge for electrochemical biosensors",
  journal="TRAC-TRENDS IN ANALYTICAL CHEMISTRY",
  year="2021",
  volume="136",
  number="116192",
  pages="1--9",
  doi="10.1016/j.trac.2021.116192",
  issn="0165-9936",
  url="https://doi.org/10.1016/j.trac.2021.116192"
}