Publication detail

The distribution of antibiotic resistance genes in chicken gut microbiota commensals

JUŘICOVÁ, H. MATIAŠOVICOVÁ, J. KUBASOVÁ, T. ČEJKOVÁ, D. RYCHLÍK, I.

Original Title

The distribution of antibiotic resistance genes in chicken gut microbiota commensals

Type

journal article in Web of Science

Language

English

Original Abstract

Antibiotic resistance in bacterial pathogens or several indicator bacteria is commonly studied but the extent of antibiotic resistance in bacterial commensals colonising the intestinal tract is essentially unknown. In this study, we aimed to investigate the presence of horizontally acquired antibiotic resistance genes among chicken gut microbiota members in 259 isolates with known whole genomic sequences. Altogether 124 isolates contained at least one gene coding for antibiotic resistance. Genes coding for the resistance to tetracyclines (detected in 101 isolates), macrolide-lincosamide-streptogramin B antibiotics (28 isolates) and aminoglycosides (25 isolates) were the most common. The most frequent tetracycline resistance genes were tet(W), tet(32), tet(O) and tet(Q). Lachnospiraceae and Ruminococcaceae frequently encoded tet(W). Lachnospiraceae commonly coded also for tet(32) and tet(O). The tet(44) gene was associated with Erysipelotrichaceae and tet(Q) was detected in the genomes of Bacteroidaceae and Porphyromonadaceae. Without any bias we have shown that antibiotic resistance is quite common in gut commensals. However, a comparison of codon usage showed that the above-mentioned families represent the most common current reservoirs but probably not the original host of the detected resistances.

Keywords

Antibiotic resistance, chicken gut commensals

Authors

JUŘICOVÁ, H.; MATIAŠOVICOVÁ, J.; KUBASOVÁ, T.; ČEJKOVÁ, D.; RYCHLÍK, I.

Released

8. 2. 2021

Publisher

Springer Nature

Location

BERLIN

ISBN

2045-2322

Periodical

Scientific Reports

Year of study

11

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

10

Pages count

10

URL

https://www.nature.com/articles/s41598-021-82640-3

Full text in the Digital Library

http://hdl.handle.net/11012/200994

BibTex

@article{BUT172114,
  author="Helena {Juřicová} and Jitka {Matiašovicová} and Tereza {Kubasová} and Darina {Čejková} and Ivan {Rychlík}",
  title="The distribution of antibiotic resistance genes in chicken gut microbiota commensals",
  journal="Scientific Reports",
  year="2021",
  volume="11",
  number="1",
  pages="1--10",
  doi="10.1038/s41598-021-82640-3",
  issn="2045-2322",
  url="https://www.nature.com/articles/s41598-021-82640-3"
}