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MAYORGA-MARTINEZ, C. ZELENKA, J. GRMELA, J. MICHÁLKOVÁ, H. RUML, T. MAREŠ, J. PUMERA, M.
Original Title
Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces
Type
journal article in Web of Science
Language
English
Original Abstract
Microscale self-propelled robots show great promise in the biomedical field and are the focus of many researchers. These tiny devices, which move and navigate by themselves, are typically based on inorganic microstructures that are not biodegradable and potentially toxic, often using toxic fuels or elaborate external energy sources, which limits their real-world applications. One potential solution to these issues is to go back to nature. Here, the authors use high-speed Aqua Sperm micromotors obtained from North African catfish (Clarias gariepinus, B. 1822) to destroy bacterial biofilm. These Aqua Sperm micromotors use water-induced dynein ATPase catalyzed adenosine triphosphate (ATP) degradation as biocompatible fuel to trigger their fast speed and snake-like undulatory locomotion that facilitate biofilm destruction in less than one minute. This efficient biofilm destruction is due to the ultra-fast velocity as well as the head size of Aqua Sperm micromotors being similar to bacteria, which facilitates their entry to and navigation within the biofilm matrix. In addition, the authors demonstrate the real-world application of Aqua Sperm micromotors by destroying biofilms that had colonized medical and laboratory tubing. The implemented system extends the biomedical application of Aqua Sperm micromotors to include hybrid robots for fertilization or cargo tasks.
Keywords
active bacterial biofilms; Aqua Sperm micromotors; biobots; nanorobots; spermatozoa; spermbots
Authors
MAYORGA-MARTINEZ, C.; ZELENKA, J.; GRMELA, J.; MICHÁLKOVÁ, H.; RUML, T.; MAREŠ, J.; PUMERA, M.
Released
1. 10. 2021
Publisher
Wiley-VCH
Location
HOBOKEN
ISBN
2198-3844
Periodical
Advanced Science
Year of study
8
Number
19
State
United States of America
Pages from
1
Pages to
7
Pages count
URL
https://onlinelibrary.wiley.com/doi/10.1002/advs.202101301
Full text in the Digital Library
http://hdl.handle.net/11012/203072
BibTex
@article{BUT173173, author="Carmen C. {Mayorga-Martinez} and Jaroslav {Zelenka} and Jan {Grmela} and Hana {Michálková} and Tomáš {Ruml} and Jan {Mareš} and Martin {Pumera}", title="Swarming Aqua Sperm Micromotors for Active Bacterial Biofilms Removal in Confined Spaces", journal="Advanced Science", year="2021", volume="8", number="19", pages="1--7", doi="10.1002/advs.202101301", issn="2198-3844", url="https://onlinelibrary.wiley.com/doi/10.1002/advs.202101301" }