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ČERNÁ, E. VOJTOVÁ, L. LIPOVÝ, B.
Original Title
Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing
Type
abstract
Language
English
Original Abstract
Wound healing is a process which requires an appropriate approach for effective and accelerated healing. Variety of materials including natural and synthetic polymers are used for the production of films, gels, hydrogels or sponges. Gum Karaya (GK) is a natural polymer, resin able to form a gel with antimicrobial properties supporting the healing process1. Here, GK was modified with synthetic hydrophilic gelling polymers and emollient component to obtain soft, elastic and transparent film via freeze-drying technique. To increase antimicrobial activity an antiseptic agent octenidine dihydrochloride (OCT) was added due to its antimicrobial effect, low absorption to the skin and no systemic toxicity. OCT is widely used antiseptics for topical wounds (acute, chronic) with antimicrobial effect against Gram-positive and Gram-negative bacteria including resistant pathogens.
Keywords
biopolymers, wound healing, Karaya gum, antimicrobial, tissue engineering
Authors
ČERNÁ, E.; VOJTOVÁ, L.; LIPOVÝ, B.
Released
19. 5. 2021
Publisher
CZECH CHEMICAL SOCIETY SYMPOSIUM SERIES
ISBN
2336-7210
Periodical
Czech Chemical Society Symposium Series
State
Czech Republic
Pages from
10
Pages to
Pages count
1
URL
http://www.interdisciplinarymeeting.cz/2021/shell/sbornik-2021.pdf
BibTex
@misc{BUT175301, author="Eva {Černá} and Lucy {Vojtová} and Břetislav {Lipový}", title="Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing", year="2021", journal="Czech Chemical Society Symposium Series", pages="10--10", publisher="CZECH CHEMICAL SOCIETY SYMPOSIUM SERIES", issn="2336-7210", url="http://www.interdisciplinarymeeting.cz/2021/shell/sbornik-2021.pdf", note="abstract" }