Publication detail

Distance-based detection in analytical flow devices: from gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices

NUCHTAVORN, N. RÝPAR, T. NEJDL, L. VACULOVIČOVÁ, M. MACKA, M.

Original Title

Distance-based detection in analytical flow devices: from gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices

Type

journal article in Web of Science

Language

English

Original Abstract

Distance-based detection (DbD) in analytical flow devices was first described in the 1930s, based on a colorimetric measurement of gas samples passing through a tube with a solid porous packing showing a color change as it reacts with the gas, with the zone length proportional to the analyte concentration. Over the following decades, DbD was introduced to a variety of formats and platforms including capillary, microfluidic chips and microfluidic paper-based analytical devices. Most of the materials are easily functionalised, and disposable. The DbD principles are based on a visible color change resulting from various reactions ranging from simple colorimetric to specific ligand or antibody binding. The immense attractivity of DbD rests in its simplicity of quantitative readout without auxiliary instrumentation. This review outlines key historical developments during 1937–2021, detection principles, driving forces, instrumental formats, and application areas. Finally, ways to overcome limitations, improve the performance and future perspectives are discussed.

Keywords

Distance-based detection; Instrumentation-free; Portable analysis; Microfluidics; Paperfluidics; Paper-based devices

Authors

NUCHTAVORN, N.; RÝPAR, T.; NEJDL, L.; VACULOVIČOVÁ, M.; MACKA, M.

Released

1. 5. 2022

ISBN

0165-9936

Periodical

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Year of study

150

Number

116581

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

13

Pages count

13

URL

BibTex

@article{BUT177482,
  author="Nantana {Nuchtavorn} and Tomáš {Rýpar} and Lukáš {Nejdl} and Markéta {Vaculovičová} and Miroslav {Macka}",
  title="Distance-based detection in analytical flow devices: from gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices",
  journal="TRAC-TRENDS IN ANALYTICAL CHEMISTRY",
  year="2022",
  volume="150",
  number="116581",
  pages="1--13",
  doi="10.1016/j.trac.2022.116581",
  issn="0165-9936",
  url="https://doi.org/10.1016/j.trac.2022.116581"
}