Publication detail

The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions

NOVÁČKOVÁ, I. HRABALOVÁ, V. SLANINOVÁ, E. SEDLÁČEK, P. OBRUČA, S.

Original Title

The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions

Type

abstract

Language

English

Original Abstract

Application of approaches of evolutionary engineering could be used to obtain microorganisms producing PHAs with required properties. Method is useful, quite simple and effective for gaining microbial strains with suitable characteristics on phenotype level (e.g. more effective growth, better productivity, ability of utilization different sources of carbon etc.) with no requirement for knowledge of genetic characteristics of original wild-type strain. Polyhydroxyalkanoates (PHAs) are microbial polymers which could replace traditional petrochemical plastics due to their favorable properties such as biodegradability and biocompatibility. Moreover, properties of PHAs depend on monomer composition, therefore materials for selected purpose could be produced, e.g. by application of evolutionary engineering tools od PHAs producing microorganisms. Considering evolutionary engineering, PHA can take a role in adaptation process due to generally enhanced robustness of PHA accumulating bacterial cells against stress.

Keywords

polyhydroxyalkanoates (PHAs), evolutionary engineering, Cupriavidus necator H16, copper stress, osmotic stress

Authors

NOVÁČKOVÁ, I.; HRABALOVÁ, V.; SLANINOVÁ, E.; SEDLÁČEK, P.; OBRUČA, S.

Released

28. 4. 2022

Publisher

MUNI PRESS

Location

Brno

ISBN

9788028000400

Book

The Biomania Student Scientific Meeting 2022 - Book of Abstracts

Edition

1.

Pages from

133

Pages to

133

Pages count

1

BibTex

@misc{BUT177706,
  author="Ivana {Nováčková} and Vendula {Hrabalová} and Eva {Slaninová} and Petr {Sedláček} and Stanislav {Obruča}",
  title="The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions",
  booktitle="The Biomania Student Scientific Meeting 2022 - Book of Abstracts",
  year="2022",
  series="1.",
  pages="133--133",
  publisher="MUNI PRESS",
  address="Brno",
  isbn="9788028000400",
  note="abstract"
}