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NOVÁČKOVÁ, I. HRABALOVÁ, V. SLANINOVÁ, E. SEDLÁČEK, P. OBRUČA, S.
Original Title
The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions
Type
abstract
Language
English
Original Abstract
Application of approaches of evolutionary engineering could be used to obtain microorganisms producing PHAs with required properties. Method is useful, quite simple and effective for gaining microbial strains with suitable characteristics on phenotype level (e.g. more effective growth, better productivity, ability of utilization different sources of carbon etc.) with no requirement for knowledge of genetic characteristics of original wild-type strain. Polyhydroxyalkanoates (PHAs) are microbial polymers which could replace traditional petrochemical plastics due to their favorable properties such as biodegradability and biocompatibility. Moreover, properties of PHAs depend on monomer composition, therefore materials for selected purpose could be produced, e.g. by application of evolutionary engineering tools od PHAs producing microorganisms. Considering evolutionary engineering, PHA can take a role in adaptation process due to generally enhanced robustness of PHA accumulating bacterial cells against stress.
Keywords
polyhydroxyalkanoates (PHAs), evolutionary engineering, Cupriavidus necator H16, copper stress, osmotic stress
Authors
NOVÁČKOVÁ, I.; HRABALOVÁ, V.; SLANINOVÁ, E.; SEDLÁČEK, P.; OBRUČA, S.
Released
28. 4. 2022
Publisher
MUNI PRESS
Location
Brno
ISBN
9788028000400
Book
The Biomania Student Scientific Meeting 2022 - Book of Abstracts
Edition
1.
Pages from
133
Pages to
Pages count
1
BibTex
@misc{BUT177706, author="Ivana {Nováčková} and Vendula {Hrabalová} and Eva {Slaninová} and Petr {Sedláček} and Stanislav {Obruča}", title="The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions", booktitle="The Biomania Student Scientific Meeting 2022 - Book of Abstracts", year="2022", series="1.", pages="133--133", publisher="MUNI PRESS", address="Brno", isbn="9788028000400", note="abstract" }