Publication detail

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

KINCL, V. VAŠINA, J. PANOVSKÝ, R. OPATŘIL, L. HOLEČEK, T. FEITOVÁ, V. SALA, M. MÁCHAL, J. KAMÍNEK, M.

Original Title

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

Type

journal article in Web of Science

Language

English

Original Abstract

Background Cadmium-Zinc-Telluride (CZT) technology allows use of low activities of radiopharmaceuticals. The aim was to verify the values of left ventricular volume parameters, obtained via ultra-low-dose thallium Single Photon Emission Computed Tomography (SPECT) using a CZT camera. Methods and Results Forty-five patients referred for an assessment of myocardial perfusion or viability imaging were examined using CZT-SPECT and 1.5 T magnetic resonance (MRI) scanner. The ultra-low-dose protocol with 0.5 Mbq 201-Tl per kg of body weight was used. The values of end-systolic (ESV) and end-diastolic volumes (EDV), left ventricular ejection fraction (EF) and myocardial mass (MM) were assessed using both techniques. A very good correlation was found between the EF, ESV, and EDV values assessed with CZT-SPECT and cardiac magnetic resonance MRI; the Pearson coefficients were 0.86, 0.95, and 0.91, respectively. A moderate correlation was found for myocardial mass, r = 0.57. Compared to MRI, SPECT systematically overestimated ESV and MM, while it underestimates the EF, with P <= .001 in all cases. There was no difference in EDV estimation. Conclusions Left ventricular volumes and ejection fraction assessed via ultra-low-dose CZT-SPECT showed very good correlation with the values obtained by MRI. A moderate correlation was found for myocardial mass.

Keywords

Left ventricular ejection fraction; Volumes; Myocardial mass; CZT; thallium

Authors

KINCL, V.; VAŠINA, J.; PANOVSKÝ, R.; OPATŘIL, L.; HOLEČEK, T.; FEITOVÁ, V.; SALA, M.; MÁCHAL, J.; KAMÍNEK, M.

Released

1. 2. 2022

Publisher

SPRINGER

Location

NEW YORK

ISBN

1071-3581

Periodical

JOURNAL OF NUCLEAR CARDIOLOGY

Year of study

29

Number

1

State

United States of America

Pages from

181

Pages to

187

Pages count

7

URL

http://link.springer.com/article/10.1007/s12350-020-02161-w

BibTex

@article{BUT180271,
  author="Marek {Sala} and Vladimír {Kincl} and Milan {Kamínek} and Jiří {Vašina} and Jan {Máchal} and Roman {Panovský} and Věra {Feitová} and Lukáš {Opatřil} and Tomáš {Holeček}",
  title="Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging",
  journal="JOURNAL OF NUCLEAR CARDIOLOGY",
  year="2022",
  volume="29",
  number="1",
  pages="181--187",
  doi="10.1007/s12350-020-02161-w",
  issn="1071-3581",
  url="http://link.springer.com/article/10.1007/s12350-020-02161-w"
}