Publication result detail

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

KINCL, V.; VAŠINA, J.; PANOVSKÝ, R.; OPATŘIL, L.; HOLEČEK, T.; FEITOVÁ, V.; SALA, M.; MÁCHAL, J.; KAMÍNEK, M.

Original Title

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

English Title

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

Type

WoS Article

Original Abstract

Background Cadmium-Zinc-Telluride (CZT) technology allows use of low activities of radiopharmaceuticals. The aim was to verify the values of left ventricular volume parameters, obtained via ultra-low-dose thallium Single Photon Emission Computed Tomography (SPECT) using a CZT camera. Methods and Results Forty-five patients referred for an assessment of myocardial perfusion or viability imaging were examined using CZT-SPECT and 1.5 T magnetic resonance (MRI) scanner. The ultra-low-dose protocol with 0.5 Mbq 201-Tl per kg of body weight was used. The values of end-systolic (ESV) and end-diastolic volumes (EDV), left ventricular ejection fraction (EF) and myocardial mass (MM) were assessed using both techniques. A very good correlation was found between the EF, ESV, and EDV values assessed with CZT-SPECT and cardiac magnetic resonance MRI; the Pearson coefficients were 0.86, 0.95, and 0.91, respectively. A moderate correlation was found for myocardial mass, r = 0.57. Compared to MRI, SPECT systematically overestimated ESV and MM, while it underestimates the EF, with P <= .001 in all cases. There was no difference in EDV estimation. Conclusions Left ventricular volumes and ejection fraction assessed via ultra-low-dose CZT-SPECT showed very good correlation with the values obtained by MRI. A moderate correlation was found for myocardial mass.

English abstract

Background Cadmium-Zinc-Telluride (CZT) technology allows use of low activities of radiopharmaceuticals. The aim was to verify the values of left ventricular volume parameters, obtained via ultra-low-dose thallium Single Photon Emission Computed Tomography (SPECT) using a CZT camera. Methods and Results Forty-five patients referred for an assessment of myocardial perfusion or viability imaging were examined using CZT-SPECT and 1.5 T magnetic resonance (MRI) scanner. The ultra-low-dose protocol with 0.5 Mbq 201-Tl per kg of body weight was used. The values of end-systolic (ESV) and end-diastolic volumes (EDV), left ventricular ejection fraction (EF) and myocardial mass (MM) were assessed using both techniques. A very good correlation was found between the EF, ESV, and EDV values assessed with CZT-SPECT and cardiac magnetic resonance MRI; the Pearson coefficients were 0.86, 0.95, and 0.91, respectively. A moderate correlation was found for myocardial mass, r = 0.57. Compared to MRI, SPECT systematically overestimated ESV and MM, while it underestimates the EF, with P <= .001 in all cases. There was no difference in EDV estimation. Conclusions Left ventricular volumes and ejection fraction assessed via ultra-low-dose CZT-SPECT showed very good correlation with the values obtained by MRI. A moderate correlation was found for myocardial mass.

Keywords

Left ventricular ejection fraction; Volumes; Myocardial mass; CZT; thallium

Key words in English

Left ventricular ejection fraction; Volumes; Myocardial mass; CZT; thallium

Authors

KINCL, V.; VAŠINA, J.; PANOVSKÝ, R.; OPATŘIL, L.; HOLEČEK, T.; FEITOVÁ, V.; SALA, M.; MÁCHAL, J.; KAMÍNEK, M.

RIV year

2023

Released

01.02.2022

Publisher

SPRINGER

Location

NEW YORK

ISBN

1071-3581

Periodical

JOURNAL OF NUCLEAR CARDIOLOGY

Volume

29

Number

1

State

United States of America

Pages from

181

Pages to

187

Pages count

7

URL

http://link.springer.com/article/10.1007/s12350-020-02161-w

BibTex

@article{BUT180271,
  author="Marek {Sala} and Vladimír {Kincl} and Milan {Kamínek} and Jiří {Vašina} and Jan {Máchal} and Roman {Panovský} and Věra {Feitová} and Lukáš {Opatřil} and Tomáš {Holeček}",
  title="Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging",
  journal="JOURNAL OF NUCLEAR CARDIOLOGY",
  year="2022",
  volume="29",
  number="1",
  pages="181--187",
  doi="10.1007/s12350-020-02161-w",
  issn="1071-3581",
  url="http://link.springer.com/article/10.1007/s12350-020-02161-w"
}