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RYŠÁVKA, P. MÁROVÁ, I.
Original Title
Targeted Modulation of Gut Microbiota by Personalized Probiotics
Type
journal article in Scopus
Language
English
Original Abstract
The current market of probiotic supplements is significantly growing although the quality and effectiveness of the commonly sold products are variable. Parameters such as the composition of each individual microbiota, strain specificity, production procedures, or storage can influence the potential positive outcome of probiotic supplements on consumers. The aim of this study was to determine changes of selected markers within the microbiota after 3 months treatment by the personalized probiotic supplement. Stool samples of 48 volunteers were analyzed by 16s ribsosomal RNA sequencing. The composition (selection of species, number of species used, and number of colony-forming units) of the probiotic mixture was designed based on the gut microbiota analysis and it was prepared for each patient separately. After 3 months of probiotic supplementation, a control sample was analyzed. Data confirmed a statistically significant increase in abundance of genera Lactobacillus and Bifidobacterium and phylum Actinobacteria. The overall number of species was also increased thus increasing the overall diversity of the microbiota, which is considered a marker of healthy gut microbiota.
Keywords
16s rRNA; Bifidobacterium; Gut; Lactobacillus; Microbiota; Probiotic
Authors
RYŠÁVKA, P.; MÁROVÁ, I.
Released
24. 10. 2022
Publisher
New Century Health Publishers
Location
Texas, USA
ISBN
1555-1431
Periodical
International Journal of Probiotics and Prebiotics
Year of study
17
Number
1
State
United States of America
Pages from
33
Pages to
41
Pages count
9
URL
https://www.scopus.com/record/display.uri?eid=2-s2.0-85132006627&origin=resultslist&sort=plf-f&src=s&st1=Marova+I&sid=ea23a94162aa2319f7c7471b6062c7b4&sot=b&sdt=b&sl=21&s=AUTHOR-NAME%28Marova+I%29&relpos=4&citeCnt=0&searchTerm=
BibTex
@article{BUT181590, author="Petr {Ryšávka} and Ivana {Márová}", title="Targeted Modulation of Gut Microbiota by Personalized Probiotics", journal="International Journal of Probiotics and Prebiotics", year="2022", volume="17", number="1", pages="33--41", doi="10.37290/ijpp2641-7197.17:33-41", issn="1555-1431", url="https://www.scopus.com/record/display.uri?eid=2-s2.0-85132006627&origin=resultslist&sort=plf-f&src=s&st1=Marova+I&sid=ea23a94162aa2319f7c7471b6062c7b4&sot=b&sdt=b&sl=21&s=AUTHOR-NAME%28Marova+I%29&relpos=4&citeCnt=0&searchTerm=" }