Publication detail

Biocompatible micromotors for biosensing

Maria-Hormigos, R. Jurado-Sanchez, B. Escarpa, A.

Original Title

Biocompatible micromotors for biosensing

Type

journal article in Web of Science

Language

English

Original Abstract

Micro/nanomotors are nanoscale devices that have been explored in various fields, such as drug delivery, environmental remediation, or biosensing and diagnosis. The use of micro/nanomotors has grown considerably over the past few years, partially because of the advantages that they offer in the development of new conceptual avenues in biosensing. This is due to their propulsion and intermixing in solution compared with their respective static forms, which enables motion-based detection methods and/or decreases bioassay time. This review focuses on the impacts of micro/nanomotors on biosensing research in the last 2 years. An overview of designs for bioreceptor attachment to micro/nanomotors is given. Recent developments have focused on chemically propelled micromotors using external fuels, commonly hydrogen peroxide. However, the associated fuel toxicity and inconvenience of use in relevant biological samples such as blood have prompted researchers to explore new micro/nanomotor biosensing approaches based on biocompatible propulsion sources such as magnetic or ultrasound fields. The main advances in biocompatible propulsion sources for micro/nanomotors as novel biosensing platforms are discussed and grouped by their propulsion-driven forces. The relevant analytical applications are discussed and representatively illustrated. Moreover, envisioning future biosensing applications, the principal advantages of micro/nanomotor synthesis using biocompatible and biodegradable materials are given. The review concludes with a realistic drawing on the present and future perspectives.

Keywords

Micromotors; Biosensing; Propulsion; Biofluid; Biomedical analysis

Authors

Maria-Hormigos, R.; Jurado-Sanchez, B.; Escarpa, A.

Released

1. 10. 2022

Publisher

SPRINGER HEIDELBERG

Location

HEIDELBERG

ISBN

1618-2650

Periodical

Analytical and Bioanalytical Chemistry

Year of study

414

Number

24

State

Federal Republic of Germany

Pages from

7035

Pages to

7049

Pages count

15

URL

https://link.springer.com/article/10.1007/s00216-022-04287-x

BibTex

@article{BUT182257,
  author="Maria-Hormigos, R. and Jurado-Sanchez, B. and Escarpa, A.",
  title="Biocompatible micromotors for biosensing",
  journal="Analytical and Bioanalytical Chemistry",
  year="2022",
  volume="414",
  number="24",
  pages="7035--7049",
  doi="10.1007/s00216-022-04287-x",
  issn="1618-2650",
  url="https://link.springer.com/article/10.1007/s00216-022-04287-x"
}